Results 61 to 70 of about 1,233,173 (377)
One of the most common means for diagnosis is through medical laboratory testing, which primarily uses venous blood as a sample. This requires an invasive method by cannulation that needs proper vein selection.
Cheng-Tang Pan+4 more
doaj +1 more source
Hemoglobin Subunit-Subunit Affinity-Determinant of Hemoglobin Formation [PDF]
Hemoglobin A₂ is often elevated in β-thalassemia and decreased in α-thalassemia. This might be due to hemoglobin subunit-subunit affinity variation. It has been inferred from the study of abnormal hemoglobins that the a subunits have higher affinity for ...
Carter, Inge R., Mansouri, Ali
core +2 more sources
The pathophysiology of extracellular hemoglobin associated with enhanced oxidative reactions
Hemoglobin (Hb) continuously undergoes autoxidation producing superoxide which dismutates into hydrogen peroxide (H2O2) and is a potential source for subsequent oxidative reactions.
J. Rifkind, J. Mohanty, E. Nagababu
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Completely noninvasive monitoring of hemoglobin concentration has not yet been fully realized in the clinical setting. This study investigates the viability of measuring hemoglobin concentration noninvasively by evaluating the performance of two types of
Panayiotis A. Kyriacou+2 more
doaj +1 more source
Oxidation of Native and Modified Hemoglobin and Myoglobin by Sodium Nitrate. Effect of Inositol Hexaphosphate [PDF]
Native and modified hemoglobin, myoglobin and a and phemoglobin subunits were oxidized by sodium nitrite at pH 6. The experiments were carried out under oxy and deoxy conditions with and without inositol hexaphosphate (IHP).
Mansouri, Ali
core +2 more sources
Oxidative stress in preeclampsia and the role of free fetal hemoglobin
Preeclampsia is a leading cause of pregnancy complications and affects 3–7% of pregnant women. This review summarizes the current knowledge of a new potential etiology of the disease, with a special focus on hemoglobin-induced oxidative stress ...
S. Hansson, Å. Nääv, L. Erlandsson
semanticscholar +1 more source
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Previous generations of hemoglobin (Hb)-based oxygen carriers (HBOCs) have been plagued by key biophysical limitations that result in severe side-effects once transfused in vivo, including protein instability, high heme oxidation rates, and nitric oxide (
Jacob Elmer, Andre F. Palmer
doaj +1 more source
BackgroundYoung children in Sub-Saharan Africa (SSA), particularly those from resource-limited settings, are heavily burdened by anemia and malaria. While malaria infected children frequently become anemic (hemoglobin < 110 g/L), anemia is a strongly ...
Tim Starck+18 more
doaj +1 more source