Results 71 to 80 of about 1,233,173 (377)

Incorporation in vitro of labeled amino acids into proteins of rabbit reticuloytes [PDF]

, 1952
Continuing our work on the incorporation of labeled amino acids into proteins (1), we have begun a study of the incorporation in vitro of C14-labeled glycine, L-histidine, L-leucine, and L-lysine into the proteins of rabbit reticulocytes.
Borsook, Henry, Deasy, Clara L., Haagen-Smit, A. J., Keighley, Geoffrey, Lowy, Peter H.   +4 more
core  

The Steady-State Transport of Oxygen through Hemoglobin Solutions [PDF]

, 1966
The steady-state transport of oxygen through hemoglobin solutions was studied to identify the mechanism of the diffusion augmentation observed at low oxygen tensions. A novel technique employing a platinum-silver oxygen electrode was developed to measure
Friedlander, S. K., Keller, K. H.
core   +2 more sources

New look at hemoglobin allostery.

Chemical Reviews, 2015
Hemoglobin (Hb) is a truly remarkable molecule. Human adult hemoglobin (Hb A) has a tetrameric structure consisting of two α-chains with 141 amino acids each and two β-chains with 146 amino acids each.
Yue Yuan, M. Tam, V. Simplaceanu, C. Ho
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Application of Carbon-Microsphere-Modified Electrodes for Electrochemistry of Hemoglobin and Electrocatalytic Sensing of Trichloroacetic Acid

Sensors, 2015
By using the hydrothermal method, carbon microspheres (CMS) were fabricated and used for electrode modification. The characteristics of CMS were investigated using various techniques.
Wen-Cheng Wang, Li-Jun Yan, Fan Shi, Xue-Liang Niu, Guo-Lei Huang, Cai-Juan Zheng, Wei Sun   +6 more
doaj   +1 more source

Improving Resulted Hemoglobin A1c Rates: A Feasibility Study for Point-of-Care Hemoglobin A1c Testing at an Urban Family Medicine Office [PDF]

, 2017
Study Aims: Our practice’s goal is to increase the number of up to date hemoglobin A1c for diabetic patients seen at JFMA in order to help improve glycemic control The aim of this study is to see if point of care (POC) hemoglobin A1C is a feasible ...
Altshuler, MD, Marc, Amadi, MD, Grace, Aragon, MD, Miranda, Askie, MD, MPH, Phoebe, Bardet, MD, Kyle, Chung, MD, Daniel, Kuperman, MD, MPH, Mariana R., Lai, MD, Sunny, Parente, MD, Laura, Parra, MD, Yury, Reaves, MD, Bruce, Woods, MD, Anna   +11 more
core   +1 more source

Aggregation of hemoglobin S and hemoglobin CHarlem with nonsickle hemoglobin in concentrated phosphate buffer [PDF]

Blood, 1980
Abstract The effect of HbA and HbF on both the aggregation and deaggregation of deoxy HbS and deoxy HbCHarlem in concentrated phosphate buffers was studied by a turbidimetric method. Although pure deoxy HbA is fully soluble in 2.4 M potassium phosphate buffer, the same concentration of deoxy HbAS was insoluble in the same buffer.
Kazuhiko Adachi, Toshio Asakura, Elias Schwartz   +2 more
openaire   +4 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2014
BACKGROUND The mechanisms by which testosterone increases hemoglobin and hematocrit remain unclear. METHODS We assessed the hormonal and hematologic responses to testosterone administration in a clinical trial in which older men with mobility ...
Eric S. Bachman, T. Travison, S. Basaria, Maithili N. Davda, W. Guo, Michelle Li, John Connor Westfall, Harold Bae, V. Gordeuk, S. Bhasin   +9 more
semanticscholar   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source