Hemoglobin: Modification, Crystallization, Polymerization (Review)
The purpose of this review is to present the most significant modifications and transformations of a hemoglobin molecule potentially related to developing a strategy of resuscitation and treatment of lifethreatening forms of anemia.
V. A. Sergunova +2 more
doaj +1 more source
Effects of ultra-purified polymerized bovine hemoglobin on local tissue oxygen tension in striated skin muscle - An efficacy study in the hamster [PDF]
The development of hemoglobin-based oxygen carriers has been propagated for replacement of the oxygen carrying properties of red blood cells for almost one century.
Botzlar, Andreas +2 more
core +1 more source
Fortuitous Discovery of a Heterozygous Hemoglobin S Disorder Associated with Hemoglobin G-Philadelphia S/G. A Case Report. [PDF]
The coexistence of two abnormal alpha and beta hemoglobin variants in the same individual is a rare and sparsely documented situation. We report the case of a diabetic child of Algerian origin, , followed in the pediatric department for insulin ...
Ahmed KHECHIBA +3 more
doaj +1 more source
Solubilization of hemoglobin S by other hemoglobins. [PDF]
The polymerization of mixtures of Hb S with hemoglobins A, A2, and F has been investigated by analysis of the proportions of S and non-S hemoglobin both in the supernate and in the pellet after centrifugation. In all cases the non-S hemoglobin was incorporated into the polymer even in the absence of hybrids in the order A > A2 > F. The solubility
R E, Benesch +3 more
openaire +2 more sources
Background: Sickle Hemoglobin is the most common pathological hemoglobin mutation worldwide which forms sickle shape or elongated forms on deoxygenation.
A Shrestha, S Karki
doaj +1 more source
Effects of the Zanzibar School-Based Deworming Program on Iron Status of Children. [PDF]
We evaluated the effects of the Zanzibar school-based deworming program on the iron status of primary school children. Parasitologic and nutritional assessments were carried out at baseline, 6 mo, and 12 mo in 4 nonprogram schools (n = 1002), 4 schools ...
Albonico, M +5 more
core +1 more source
Interaction Between Human Hemoglobin Variants and Hemoglobin S
SummarySeven abnormal hemoglobins were investigated for an effect on the gelation of Hb S in the deoxy- or oxy-conformation. A positive effect (decreased MGC) was associated with substitution of Glu β6, Glu β26 and Glu β121. No difference was observed between the deoxy- or oxy-hemoglobins except in the case of Hb N-Baltimore which, in the deoxy state ...
J, Kumpati, T H, Hiusman, G D, Efremov
openaire +2 more sources
Physical and chemical processes and the morphofunctional characteristics of human erythrocytes in hyperglycaemia [PDF]
Background: This study examines the effect of graduated hyperglycaemia on the state and oxygen-binding ability of hemoglobin, the correlation of phospholipid fractions and their metabolites in the membrane, the activity of proteolytic enzymes and the ...
Bourdon, Jean Christophe +11 more
core +5 more sources
ßS-Haplotypes in sickle cell anemia patients from Salvador, Bahia, Northeastern Brazil
ßS-Globin haplotypes were studied in 80 (160 ßS chromosomes) sickle cell disease patients from Salvador, Brazil, a city with a large population of African origin resulting from the slave trade from Western Africa, mainly from the Bay of Benin ...
M.S. Gonçalves +12 more
doaj +1 more source
Vitamin A Supplementation and Other Predictors of Anemia Among Children from Dar Es Salaam, Tanzania. [PDF]
The associations of hemoglobin, hematocrit, and packed cell volume with socioeconomic factors, malaria, human immunodeficiency virus (HIV) infection, and nutritional status were examined among 687 children admitted to hospital with pneumonia ...
Fawzi, W W +4 more
core +1 more source

