Prevalence of hemoglobin S trait among blood donors: a cross-sectional study. [PDF]
BackgroundSickle cell trait (SCT) or Hemoglobin S (HbS) trait which is due to inheritance of an abnormal hemoglobin (Hb) gene from one parent and a normal gene from the other has been known to be common among people of African descent.
Antwi-Baffour S +4 more
europepmc +2 more sources
Novel Insights Into the Protective Role of Hemoglobin S and C Against Plasmodium falciparum Parasitemia. [PDF]
Although hemoglobin S (HbS) and hemoglobin C (HbC) are well known to protect against severe Plasmodium falciparum malaria, conclusive evidence on their role against infection has not yet been obtained.
Mangano VD +14 more
europepmc +2 more sources
Background: Measurement of A1c using the Sebia Capillarys-2 capillary electrophoresis (A1c CE) involves relative quantitative measurements of peaks for hemoglobins A1c, A, A2.
Catherine M. Tucker, Douglas F. Stickle
doaj +1 more source
Acceleration of hemoglobin C crystallization by hemoglobin S [PDF]
We previously reported that circulating hemoglobin (Hb) CC erythrocytes contain oxygenated HbC crystals with little or no HbF and that HbF inhibits in vitro crystallization of HbC. We now report that HbS accelerates in vitro crystallization of HbC. Crystals were formed in 1.8 mol/L potassium phosphate buffer, pH 7.4, at 30 degrees C and were counted in
M J, Lin, R L, Nagel, R E, Hirsch
openaire +2 more sources
Solubilization of hemoglobin S by other hemoglobins. [PDF]
The polymerization of mixtures of Hb S with hemoglobins A, A2, and F has been investigated by analysis of the proportions of S and non-S hemoglobin both in the supernate and in the pellet after centrifugation. In all cases the non-S hemoglobin was incorporated into the polymer even in the absence of hybrids in the order A > A2 > F. The solubility
R E, Benesch +3 more
openaire +2 more sources
Hematological Changes in Women and Infants Exposed to an AZT-Containing Regimen for Prevention of Mother-to-child-transmission of HIV in Tanzania. [PDF]
Tanzanian guidelines for prevention of mother-to-child-transmission of HIV (PMTCT) recommend an antiretroviral combination regimen involving zidovudine (AZT) during pregnancy, single-dosed nevirapine at labor onset, AZT plus Lamivudine (3TC) during ...
A Alioum +31 more
core +8 more sources
Comparative Oxidation of Hemoglobins A and S [PDF]
AbstractThe mutant hemoglobin S (HbS) previously was reported to undergo accelerated autooxidation during incubation in vitro. However, subsequent observations have raised the possibility that this might be explained by adventitious association of molecular iron with HbS, rather than reflecting an inherent property of HbS.
K, Sheng, M, Shariff, R P, Hebbel
openaire +3 more sources
Hemoglobin: Modification, Crystallization, Polymerization (Review)
The purpose of this review is to present the most significant modifications and transformations of a hemoglobin molecule potentially related to developing a strategy of resuscitation and treatment of lifethreatening forms of anemia.
V. A. Sergunova +2 more
doaj +1 more source
Hematology, Biochemistry and Serum Protein Analyses of Antarctic and non-Antarctic Skuas [PDF]
Determination of hematological and biochemical parameters provides important data to assess the physiological condition in wild birds. Therefore, to carry out ecophysiology or conservation studies it is essential to establish baseline physiological ...
Ibañez, Andres Esteban +3 more
core +2 more sources
Fortuitous Discovery of a Heterozygous Hemoglobin S Disorder Associated with Hemoglobin G-Philadelphia S/G. A Case Report. [PDF]
The coexistence of two abnormal alpha and beta hemoglobin variants in the same individual is a rare and sparsely documented situation. We report the case of a diabetic child of Algerian origin, , followed in the pediatric department for insulin ...
Ahmed KHECHIBA +3 more
doaj +1 more source

