Results 11 to 20 of about 21,841,476 (331)
Relative Affinity of Hemoglobin S and Hemoglobin A for Carbon Monoxide and Oxygen
Clinical Chemistry, 1974 Abstract The relative affinity constants of hemolysates from individuals with hemoglobins A, S, or AS have been measured at 37 and 26 ° C. Observed values of all hemoglobin types were the same at both temperatures, K37 = 230, K26 = 296. Control measurements on whole blood containing Hb A gave values of K37 = 222.
F L, Rodkey +3 more
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Revista Brasileira de Hematologia e Hemoterapia, 2007 A hemoglobina S (HbS) é uma das alterações hematológicas hereditárias de maior freqüência. No Brasil, a prevalência do traço falciforme (HbAS) varia de 2% a 8%.
Mitiko Murao, Maria Helena C. Ferraz
doaj +2 more sources
Voxelotor: A Hemoglobin S Polymerization Inhibitor for the Treatment of Sickle Cell Disease. [PDF]
J Adv Pract Oncol, 2020 Sickle cell disease (SCD) affects millions of people throughout the world. Hemoglobin S (HbS) polymerization is the fundamental cause of SCD pathophysiology, which leads to hemolysis, increased viscosity, and acute vaso-occlusive episodes.
Yenamandra A, Marjoncu D.
europepmc +2 more sources
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease. [PDF]
Proc Natl Acad Sci U S A, 2020 Significance The root cause of pathology in sickle cell disease is the polymerization of the mutant hemoglobin S upon deoxygenation in the tissues to form fibers.
Henry ER +13 more
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Hemoglobin S polymerization and sickle cell disease: A retrospective on the occasion of the 70th anniversary of Pauling's Science paper. [PDF]
Am J Hematol, 2020 70 years ago, Linus Pauling, the legendary genius of 20th century chemistry, published his famous work on the molecular cause of sickle cell disease, a paper that gave birth to what is now called molecular medicine.
Eaton WA.
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Low proportions of glycosylated hemoglobin associated with hemoglobin S and hemoglobin C.
Clinical Chemistry, 1979 Abstract Using a cation-exchange chromatographic method, we found normal or subnormal values for glycosylated hemoglobin in a few diabetic patients with persistent hyperglycemia. Subsequent investigations revealed that these unexpected results had originated from black patients with diabetes.
H. Aleyassine
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Voxelotor (GBT440) produces interference in measurements of hemoglobin S. [PDF]
Clin Chim Acta, 2018 A 35-y-old African-American male presented to the emergency department at Vanderbilt University Medical Center for treatment of sickle cell pain crisis.
Rutherford NJ +3 more
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Hemoglobin S Measurement [PDF]
Definitions, 2020 The determination of the amount of hemoglobin S present in a sample.
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Hemoglobin S-nitrosylation plays an essential role in cardioprotection. [PDF]
J Clin Invest, 2016 Zhang R +3 more
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