Results 261 to 270 of about 21,841,476 (331)

The Role of Platelet-to-Neutrophil Ratio as a Biomarker for Pulmonary Hypertension in Sickle Cell Disease Patients: A Retrospective Cohort Study. [PDF]

open access: yesMedicina (Kaunas)
Alwaheed AJ   +12 more
europepmc   +1 more source

Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform

open access: yesAdvanced Science, EarlyView.
We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng   +5 more
wiley   +1 more source

Sickle cell disease implicated in the development of severe dengue: A pediatric case series. [PDF]

open access: yesRev Soc Bras Med Trop
Hernández MR   +3 more
europepmc   +1 more source

Hemoglobin S, the Pneumococcus, and the Spleen

Archives of Pediatrics & Adolescent Medicine, 1972
Hemoglobin S (Hb S) and selected bacteria are among medicine's more enigmatic bedfellows. The clinical importance of this association is underscored by the recognition of infection as the major presenting manifestation of sickle cell anemia in early childhood, the most common complication requiring hospitalization and the most common cause of death at ...
J. Lukens
openaire   +3 more sources

Surface activity of hemoglobin S and other human hemoglobin variants

Biochimica et Biophysica Acta (BBA) - Protein Structure, 1976
The kinetics of surface pressure change (deltapi vs. t isotherms) were determined for several single point mutations of the human hemoglobin system. It was observed that hemoglobin S and hemoglobin CHarlem (both containing beta6 Glu leads to Val substitutions) have a specific behavior at the water-air interface: their extent of surface pressure change ...
D, Elbaum   +3 more
openaire   +3 more sources

A new diagnostic test for hemoglobin S

The Journal of Pediatrics, 1970
Summary A differential solubility method for determining the presence of sickle hemoglobin S was investigated. The method was found to be simple and accurate, using either venous anticoagulated blood or fingerprick.
M S, Ballard   +3 more
openaire   +3 more sources

Kinetics of polymerization of deoxyhemoglobin S and mixtures of hemoglobin A and hemoglobin S at high hemoglobin concentrations

Archives of Biochemistry and Biophysics, 1977
Abstract Transverse water proton relaxation times ( T 2 ) have been measured as a function of time after deoxygenation of solutions containing hemoglobin S. The shortened T 2 values observed upon deoxygenation of hemoglobin S result from an increase in the correlation time ( τ c ) of the water fraction irrotationally bound to deoxyhemoglobin S ...
G L, Cottam   +2 more
openaire   +2 more sources

Home - About - Disclaimer - Privacy