Results 21 to 30 of about 732,010 (281)

Hemoglobin SE disease in Hatay, in the southern part of Turkey

Thalassemia Reports, 2015
Double heterozygosity for hemoglobin (Hb) E and S, known as HbSE disease, is a rare, clinically benign condition involving mild hemolysis. Only 25 cases have been reported to date.
Can Acipayam, Gonul Oktay, Gul Ilhan, Mehmet Akif Çürük   +3 more
doaj   +1 more source

Mechanistic Insight into the Enzymatic Reduction of Truncated Hemoglobin N of Mycobacterium tuberculosis: role of the CD loop and pre-A Motif in electron cycling [PDF]

, 2014
Background: The HbN of Mycobacterium tuberculosis carries a potent nitric-oxide dioxygenase activity despite lacking a reductase domain. Results: The NADH-ferredoxin reductase system acts as an efficient partner for the reduction of HbN.
Bidon Chanal, Axel, Datta, H., Dikshit, Kanak L., Estrin, Dario Ariel, Hade, Mangesh Dattu, Luque, F. Javier, Marti, Marcelo Adrian, Oliveira, Ana, Parkesh, R., Petruk, Ariel Alcides, Sethi, Deepti, Singh, Sandeep, Thakur, Naveen   +12 more
core   +2 more sources

Oxidized Mutant Human Hemoglobins S and E Induce Oxidative Stress and Bioenergetic Dysfunction in Human Pulmonary Endothelial Cells

Frontiers in Physiology, 2017
Cell free hemoglobin (Hb), becomes oxidized in the circulation during hemolytic episodes in sickle cell disease (SCD) or thalassemia and may potentially cause major complications that are damaging to the vascular system.
Sirsendu Jana, Fantao Meng, Rhoda E. Hirsch, Joel M. Friedman, Abdu I. Alayash   +4 more
doaj   +1 more source

Evaluation of beta-galactosidase activity in tissue in the presence of blood [PDF]

, 2000
The reporter gene for beta -galactosidase is frequently used to determine the efficiency of gene transfer in arteries. However, blood is often present in arterial explants and may compromise the results by the presence of hemoglobin. The light absorption
Armeanu, Sorin, Nikol, Sigrid, Pelisek, Jaroslav   +2 more
core   +1 more source

MR imaging–derived oxygen-hemoglobin dissociation curves and fetal-placental oxygen-hemoglobin affinities [PDF]

, 2016
PURPOSE: To generate magnetic resonance (MR) imaging–derived, oxygen-hemoglobin dissociation curves and to map fetal-placental oxygen-hemoglobin affinity in pregnant mice noninvasively by combining blood oxygen level–dependent (BOLD) T2* and oxygen ...
Akselrod-Ballin, Ayelet, Avni, Reut, Biton, Inbal, Cohen, Yonni, Garbow, Joel R, Golani, Ofra, Neeman, Michael   +6 more
core   +2 more sources

Vascular risk factors and diabetic neuropathy [PDF]

, 2005
Background: Other than glycemic control, there are no treatments for diabetic neuropathy. Thus, identifying potentially modifiable risk factors for neuropathy is crucial.
Chaturvedi, N., Eaton, S.E.M., Fuller, J.H., Ionescu-Tirgoviste, C., Manes, C., Tesfaye, S., Ward, J.D., Witte, D.R.   +7 more
core   +1 more source

Validation and determination of a reference interval for Canine HbA1c using an immunoturbidimetric assay [PDF]

, 2017
Background: Hemoglobin A1c (HbA1c) provides a reliable measure of glycemic control over 2–3 months in human diabetes mellitus. In dogs, presence of HbA1c has been demonstrated, but there are no validated commercial assays. Objective: The purpose
Goemans, Anne F., Ramsey, Ian K., Spence, Susanna J.   +2 more
core   +1 more source

Therapeutic red blood cell exchange in a sickle cell disease patient with acute bone pain crisis: Our experience in a tertiary care center

Asian Journal of Transfusion Science
Transfusion therapy remains the main stay of treatment for patients with sickle cell anemia for several years. However, repeated transfusions might result in iron overload and alloimmunization in sickle cell disease (SCD) patients.
Suresh Kumar Iyyapan, Hari Haran Annadurai, Gokhula Prasath Thangavel, Hemamalini Natesan   +3 more
doaj   +1 more source

Erythrocyte enrichment in hematopoietic progenitor cell cultures based on magnetic susceptibility of the hemoglobin [PDF]

, 2012
Using novel media formulations, it has been demonstrated that human placenta and umbilical cord blood-derived CD34+ cells can be expanded and differentiated into erythroid cells with high efficiency.
Irene Georgakoudi, Jeffrey J. Chalmers, Lee R. Moore, Lin Kang, Maciej Zborowski, Marina V. Kameneva, Rui Zhao, Stewart Abbot, Vanessa Voskinarian-Berse, Xiaokui Zhang, Xiaoxia Jin   +10 more
core   +4 more sources

Multispectral imaging for MicroChip electrophoresis enables point-of-care newborn hemoglobin variant screening

Heliyon, 2022
Hemoglobin (Hb) disorders affect nearly 7% of the world’s population. Globally, around 400,000 babies are born annually with sickle cell disease (SCD), primarily in sub-Saharan Africa where morbidity and mortality rates are high.
Ran An, Yuning Huang, Anne Rocheleau, Alireza Avanaki, Priyaleela Thota, Qiaochu Zhang, Yuncheng Man, Zoe Sekyonda, Catherine I. Segbefia, Yvonne Dei-Adomakoh, Enoch Mensah, Kwaku Ohene-Frempong, Isaac Odame, Amma Owusu-Ansah, Umut A. Gurkan   +14 more
doaj   +1 more source