Results 21 to 30 of about 38,246 (331)

COVID-19 infection and beta thalassemia; a single center experience in Iran [PDF]

Journal of Preventive Epidemiology, 2021
Introduction: COVID-19 infection is a contagious acute respiratory syndrome, leading to a high mortality rate; it is also a systemic disease, and all people are at risk of being infected, including hemoglobinopathies patients.
Roya Salehi Kahyesh, Arash Alghasi, Bijan Keikhaei Dehdezi, Adeleh Khazami, Marzeieh Abbasi Nasab   +4 more
doaj   +1 more source

A genome-editing strategy to treat β-hemoglobinopathies that recapitulates a mutation associated with a benign genetic condition

Nature Medicine, 2016
Yu Yao, Yong-Dong Wang, Kaitly J Woodard
exaly   +2 more sources

Pubertal Assessment and Growth in Patients With Hemoglobinopathies: A Longitudinal Multicenter Study on the Association With Ferritin Levels [PDF]

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Although Advancements in the Treatment of Hemoglobinopathies have Considerably Increased Life Expectancy, Hormonal and Pubertal Development Have Been Continuously Affected by Complications From Transfusion‐Related Iron Overload and Cytotoxic Therapies.
Jill Dülberg, Concepción Prados Sánchez, Vivienne Salow, Anne‐Catherine Radauer‐Plank, Anja Borgmann‐Staudt, Holger Cario, Miriam Diepold, Beatrice Drexler, Laura Infanti, N. Dietliker, Linet Njue, Lena Oevermann, Alicia Rovó, Katrin Scheinemann, Magdalena Balcerek, Tamara Diesch   +15 more
openalex   +2 more sources

HELIOS Action: Advancing research, education, and equity in hemoglobinopathies across Europe and beyond. [PDF]

Hemasphere
HemaSphere, Volume 9, Issue 12, December 2025.
Chatzimatthaiou S, Bonifazi F, Gimbert AC, Colombatti R, Cremonesi F, Glenthøj A, Mezzalira E, Stephanou C, Traeger-Synodinos J, Antic D, Durmaz B, Gavriilaki E, Inusa B, Landi A, Pellegrini M, Basile F, Muth S, Cario H, Katsantoni E, Ruhluel D, Lederer CW, Mañú-Pereira MDM, Kountouris P.   +22 more
europepmc   +2 more sources

Epidemiological surveillance of SARSCov2 in β-Thalassemia Patients in the last two years: reinfection rate, insights and future challenges

Mediterranean Journal of Hematology and Infectious Diseases, 2023
Background: Although the association between comorbidities and the severity of COVID-19 infection has been extensively discussed, data on COVID-19 and hemoglobinopathies are still limited.
Lorenza Torti, Francesco Sorrentino, Laura Maffei, Paolo De Fabritiis, Elisabetta Abruzzese   +4 more
doaj   +1 more source

Insights Into Hemoglobinopathies in Spain: A Comprehensive Review. [PDF]

EJHaem
Corrons JV.
europepmc   +3 more sources

Endocrinopathies in Hemoglobinopathies: What Is the Role of Iron?

International Journal of Molecular Sciences, 2023
Hemoglobinopathies, including β-thalassemia and sickle cell disease (SCD), are common genetic blood disorders. Endocrine disorders are frequent manifestations of organ damage observed mainly in patients with β-thalassemia and rarely in SCD. Iron overload,
Paschalis Evangelidis, T. Venou, Barmpageorgopoulou Fani, E. Vlachaki, E. Gavriilaki   +4 more
semanticscholar   +1 more source

Precision Editing as a Therapeutic Approach for β-Hemoglobinopathies

International Journal of Molecular Sciences, 2023
Beta-hemoglobinopathies are the most common genetic disorders worldwide, caused by a wide spectrum of mutations in the β-globin locus, and associated with morbidity and early mortality in case of patient non-adherence to supportive treatment.
K. Paschoudi, E. Yannaki, N. Psatha
semanticscholar   +1 more source

Epigenetic Regulation of β-Globin Genes and the Potential to Treat Hemoglobinopathies through Epigenome Editing

Genes, 2023
Beta-like globin gene expression is developmentally regulated during life by transcription factors, chromatin looping and epigenome modifications of the β-globin locus.
Letizia Fontana, Zoe Alahouzou, A. Miccio, P. Antoniou   +3 more
semanticscholar   +1 more source

Hb^Adrian (α1:c.251del, p.Leu84Argfs*19)—A Novel Pathogenic Variant in the α1-Globin Gene Associated with Microcytosis from the North of Iran

Thalassemia Reports, 2023
Background: Alpha thalassemia is one of the most common human genetic abnormalities. More than 400 different variations of the α-globin protein have been introduced, most of which are not associated with noticeable clinical manifestations.
Hossein Jalali, Hossein Karami, Mahan Mahdavi, Mohammad Reza Mahdavi   +3 more
doaj   +1 more source