Results 81 to 90 of about 23,191 (234)
CONTEXT: Hemoglobinopathies constitute the world's most common genetically inherited red blood cell disorder. Screening and accurate identification of hemoglobin (Hb) variants have become increasingly important in antenatal diagnosis and prevention of Hb
Sandeep Warghade+9 more
semanticscholar +1 more source
Time in range—A new gold standard in type 2 diabetes research?
Abstract Glycated haemoglobin (HbA1c) is currently the gold standard outcome measure for type 2 diabetes trials. Time in range is a continuous glucose monitoring (CGM) metric defined as the proportion of time in euglycemia (3.9–10.0 mmol/L) and may be valuable not only in type 1 diabetes clinical trials but also as an endpoint in type 2 diabetes trials.
Ashni Goshrani+3 more
wiley +1 more source
Type and frequency of hemoglobinopathies, diagnosed in the area of Karachi, in Pakistan
Hemoglobinopathies are one of the major problems in Pakistan. A retrospective analysis of blood samples of 2731 patients from 2010 to 2014 was done at National Institute of Blood Disease & Bone Marrow Transplantation for the workup of anemia or other ...
Shaista Shabbir+12 more
doaj +1 more source
Abstract Background People living with HIV have a greater prevalence of anaemia compared with people without HIV, which increases the risk of associated morbidity and premature mortality. Risk factors for anaemia among people living with HIV have changed in recent decades due to new antiretroviral therapy (ART), increased uptake of ART and increasing ...
George B. Freer+4 more
wiley +1 more source
CONTEXT: Hemoglobinopathies are the most common heterogeneous group of monogenetic disorder in the world and its prevalence varies with geographical regions.
Virender Singh+4 more
doaj +1 more source
Economic burden of sickle cell disease in Australia
Abstract Background Sickle cell disease (SCD) is an inherited condition that impairs red blood cell function, posing a substantial health burden on patients. As the prevalence of SCD in Australia rises due to migration, discussions surrounding treatment and management strategies are becoming more prominent. Aims Australia lacks a dedicated study on the
Steve Nwokeocha+16 more
wiley +1 more source
GENE THERAPY IN THALASSEMIA AND HEMOGLOBINOPATHIES
Sickle cell disease (SCD) and ß-thalassemia represent the most common hemoglobinopathies caused, respectively, by the alteration of structural features or deficient production of the ß-chain of the Hb molecule.
Laura Breda+2 more
doaj +1 more source
Circulating erythropoietic precursors assessed in culture: characterization in normal men and patients with hemoglobinopathies [PDF]
Makio Ogawa+4 more
openalex +1 more source
This meta‐analysis demonstrates a significant association between maternal anaemia and a 30% increased risk of intrauterine growth restriction (IUGR). These findings emphasize the need for early identification and effective management of anaemia during pregnancy to improve foetal outcomes.
Rajeev Jayalakshmi+14 more
wiley +1 more source
Background: Nearly 226 million carriers of thalassemias and abnormal hemoglobin are present worldwide according to the World Health Organization (WHO). The laboratory plays an important role in the investigation of the thalassemias and hemoglobinopathies.
R Jha
doaj +1 more source