Results 81 to 90 of about 23,191 (234)

Prevalence of hemoglobin variants and hemoglobinopathies using cation-exchange high-performance liquid chromatography in central reference laboratory of India: A report of 65779 cases

open access: yesJournal of Laboratory Physicians, 2018
CONTEXT: Hemoglobinopathies constitute the world's most common genetically inherited red blood cell disorder. Screening and accurate identification of hemoglobin (Hb) variants have become increasingly important in antenatal diagnosis and prevention of Hb
Sandeep Warghade   +9 more
semanticscholar   +1 more source

Time in range—A new gold standard in type 2 diabetes research?

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2342-2362, May 2025.
Abstract Glycated haemoglobin (HbA1c) is currently the gold standard outcome measure for type 2 diabetes trials. Time in range is a continuous glucose monitoring (CGM) metric defined as the proportion of time in euglycemia (3.9–10.0 mmol/L) and may be valuable not only in type 1 diabetes clinical trials but also as an endpoint in type 2 diabetes trials.
Ashni Goshrani   +3 more
wiley   +1 more source

Type and frequency of hemoglobinopathies, diagnosed in the area of Karachi, in Pakistan

open access: yesCogent Medicine, 2016
Hemoglobinopathies are one of the major problems in Pakistan. A retrospective analysis of blood samples of 2731 patients from 2010 to 2014 was done at National Institute of Blood Disease & Bone Marrow Transplantation for the workup of anemia or other ...
Shaista Shabbir   +12 more
doaj   +1 more source

Trends in prevalence of anaemia among people living with HIV in the UK: 20 cross‐sectional analyses using population‐based electronic primary healthcare records

open access: yesHIV Medicine, EarlyView.
Abstract Background People living with HIV have a greater prevalence of anaemia compared with people without HIV, which increases the risk of associated morbidity and premature mortality. Risk factors for anaemia among people living with HIV have changed in recent decades due to new antiretroviral therapy (ART), increased uptake of ART and increasing ...
George B. Freer   +4 more
wiley   +1 more source

Prevalence of hemoglobinopathies using high-performance liquid chromatography as diagnostic tool in anemic patients of tertiary care center of Western India

open access: yesAsian Journal of Transfusion Science
CONTEXT: Hemoglobinopathies are the most common heterogeneous group of monogenetic disorder in the world and its prevalence varies with geographical regions.
Virender Singh   +4 more
doaj   +1 more source

Economic burden of sickle cell disease in Australia

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Sickle cell disease (SCD) is an inherited condition that impairs red blood cell function, posing a substantial health burden on patients. As the prevalence of SCD in Australia rises due to migration, discussions surrounding treatment and management strategies are becoming more prominent. Aims Australia lacks a dedicated study on the
Steve Nwokeocha   +16 more
wiley   +1 more source

GENE THERAPY IN THALASSEMIA AND HEMOGLOBINOPATHIES

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2009
Sickle cell disease (SCD) and ß-thalassemia represent the most common hemoglobinopathies caused, respectively, by the alteration of structural features or deficient production of the ß-chain of the Hb molecule.
Laura Breda   +2 more
doaj   +1 more source

The Effect of Maternal Haemoglobinopathies and Iron Deficiency Anaemia on Foetal Growth Restriction: A Systematic Review and Meta‐Analysis

open access: yesMaternal &Child Nutrition, EarlyView.
This meta‐analysis demonstrates a significant association between maternal anaemia and a 30% increased risk of intrauterine growth restriction (IUGR). These findings emphasize the need for early identification and effective management of anaemia during pregnancy to improve foetal outcomes.
Rajeev Jayalakshmi   +14 more
wiley   +1 more source

Distribution of hemoglobinopathies in patients presenting for electrophoresis and comparison of result with High performance liquid chromatography

open access: yesJournal of Pathology of Nepal, 2015
Background: Nearly 226 million carriers of thalassemias and abnormal hemoglobin are present worldwide according to the World Health Organization (WHO). The laboratory plays an important role in the investigation of the thalassemias and hemoglobinopathies.
R Jha
doaj   +1 more source

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