Results 11 to 20 of about 1,783,252 (315)

In vitro determination of hemoglobin A1c for diabetes diagnosis and management: technology update [PDF]

open access: yes, 2014
It is fascinating to consider the analytical improvements that have occurred since glycated hemoglobin was first used in routine clinical laboratories for diabetes monitoring around 1977; at that time methods displayed poor precision, there were no ...
English, Emma   +2 more
core   +1 more source

Severe Hemolytic Anemia due to De novo Hemoglobin Sabine in an argentinian newborn: first case in South America [PDF]

open access: yes, 2015
Hemoglobin (Hb) Sabine is an unstable Hb variant that causes hemolytic anemia in heterozygous state, with inclusion bodies in the red blood cells (RBC). This hemoglobin is the result of a point mutation at codon 91(CTG)(CCG) of the beta-globin gene.
Acosta, Irma   +9 more
core   +1 more source

Heterozigose para hemoglobinopatias em doadores de sangue do Centro de Hemoterapia de Sergipe Heterozigosity to hemoglobinopathies in blood donors from the Hemotherapy Center in Sergipe, NE-Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2006
As hemoglobinopatias, distúrbios geneticamente determinados da hemoglobina (Hb) humana, estão presentes com freqüência elevada em várias partes do mundo, sendo que no Brasil as Hb anormais S e C são as mais prevalentes.
Wanessa L. P. Vivas   +3 more
doaj   +1 more source

Validation and determination of a reference interval for Canine HbA1c using an immunoturbidimetric assay [PDF]

open access: yes, 2017
Background: Hemoglobin A1c (HbA1c) provides a reliable measure of glycemic control over 2–3 months in human diabetes mellitus. In dogs, presence of HbA1c has been demonstrated, but there are no validated commercial assays. Objective: The purpose
Goemans, Anne F.   +2 more
core   +1 more source

Reaction trajectory revealed by a joint analysis of protein data bank. [PDF]

open access: yesPLoS ONE, 2013
Structural motions along a reaction pathway hold the secret about how a biological macromolecule functions. If each static structure were considered as a snapshot of the protein molecule in action, a large collection of structures would constitute a ...
Zhong Ren
doaj   +1 more source

NEW REPORT OF KOLN HEMOGLOBIN FROM COUNTRYSIDE/INTERIOR OF SÃO PAULO

open access: yesHematology, Transfusion and Cell Therapy, 2021
Introduction: Hemoglobinopathies are considered a major public health problem in many countries, including Brazil, a fact explained by their frequency, genetic diversity and clinical importance. The unstable hemoglobin group is associated with congenital
JO Rios, LR Pereira, CR Bonini-Domingos
doaj   +1 more source

Interação entre Hb C [beta6(A3)Glu>Lys] e IVS II-654 (C>T) beta-talassemia no Brasil Hb C [beta6(A3)Glu>Lys] and IVS II - 654 (C>T) beta thalassemia interaction in Brazil

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2003
Thalassemias are a heterogeneous group of inherited disorders characterized by a microcytic hypochromic anemia and an imbalance in the synthesis of the globin-chains. Hb C is the second most frequently variant of hemoglobin found in Brazil.
Claudia R. Bonini-Domingos   +4 more
doaj   +1 more source

Chemical Characterization and Subunit Hybridization of Human Hemoglobin H and Associated Compounds [PDF]

open access: yes, 1963
Two abnormal hemoglobin components have been detected in association with thalassemiahemoglobin H disease. These components, as well as the major hemoglobin component, have been chemically characterized by determination of the amino acid composition, N ...
Jones, Richard T., Schroeder, W. A.
core   +1 more source

The first Chinese case of unstable Hemoglobin Santa Ana detected by capillary electrophoresis: a case report and literature review

open access: yesHematology, 2022
Hemoglobin Santa Ana [β88(F4)Leu→Pro (CTG > CCG) HBB: c.266T > C] is an unstable hemoglobin variant characterized by a substitution of the amino acid leucine by proline at the 88th position of the β-globin chain.
Li Du   +8 more
doaj   +1 more source

STUDIES ON ABNORMAL HEMOGLOBIN

open access: yesNihon Naika Gakkai Zasshi, 1967
本邦では1957年ごろより異常血色素の本格的検索がはじめられたが,著者は戦後わが国に残された混血児達により,従来本邦に存在しなかつた異常血色素の遺伝因子が導入される可能性を考え,その実態を明らかにせんとして混血児179名について異常血色素の検索を行ない,また同時に東京,神奈川在住本邦人3000余名についても異常血色素の検索を行なつた.その結果,本邦人3000余名中よりは1例も異常血色素を確認できなかつたが,混血児179名中よりは2例に異常血色素を確認した.この比率は約1.1%である.
openaire   +2 more sources

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