Results 41 to 50 of about 89,531 (289)

Evolutionary and Functional Relationships in the Truncated Hemoglobin Family [PDF]

, 2016
Predicting function from sequence is an important goal in current biological research, and although, broad functional assignment is possible when a protein is assigned to a family, predicting functional specificity with accuracy is not straightforward ...
Boechi, Leonardo, Bustamante, Juan Pablo, Estrin, Dario Ariel, Marti, Marcelo Adrian, Radusky, Leandro Gabriel, Ten Have, Arjen   +5 more
core   +3 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Determination of Beta Thalassemia trait and abnormal Hemoglobin variant frequency

Iberoamerican Journal of Medicine
Introduction: Hemoglobinopathies are among the most common hereditary disorders globally, classified into thalassemias and abnormal hemoglobins. Abnormal hemoglobins arise from genetic alterations like point mutations, insertions, or deletions, with Hb S,
Miraç Seher Helvacı, Melih Tekinay, Okan Yılmaz, Mustafa Şahin, Öngen İpek, Eren Vurgun, Okan Dikker, Hüseyin Dağ   +7 more
doaj   +1 more source

Studies on the Hemoglobin of Cooley's Anemia and Cooley's Trait [PDF]

, 1952
The diseases sickle cell anemia and Cooley's anemia (also known as thalassemia or Mediterranean anemia) have associated with them "minor" or "trait" forms of the disease in which the symptomatology is minimal, and the abnormalities in the red cells are ...
Rich, Alexander
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Neocytolysis: How to Get Rid of the Extra Erythrocytes Formed by Stress Erythropoiesis Upon Descent From High Altitude

Frontiers in Physiology, 2018
Neocytolysis is the selective destruction of those erythrocytes that had been formed during stress-erythropoiesis in hypoxia in order to increase the oxygen transport capacity of blood.
Heimo Mairbäurl
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Disease Activity in Rheumatoid Arthritis Patients Stratified by Hemoglobin Levels: A Multi-center Study

Oman Medical Journal
Objectives: Hemoglobin (Hb) level and its relation to rheumatoid arthritis (RA) is multifactorial. The primary aim of this study was to examine the association between Hb levels and disease activity in patients with RA.
Maryam Salah Al-Mazedi, Rajesh Rajan, Adeeba Al-Herz, Ahmad Alsaber, Mohammed Al-Jarallah, Raja Dashti, Parul Setiya, Khulood Saleh, Adel Al-Awadhi, Waleed Al-Kandari, Eman Hasan, Khaled Mokaddem, Aqeel Ghanem, Ahmad Alenizi, Kobalava D. Zhanna, Laura Al Obaid   +15 more
doaj   +1 more source

A comparative study of norethisterone and combined oral contraceptive pill in the treatment of dysfunctional uterine bleeding

CHRISMED Journal of Health and Research, 2019
Background: A significant percentage of women in India suffer from dysfunctional uterine bleeding (DUB), which has a negative impact on physical and social life.
Sayantan Sen, Tapan Kumar Mandal, Arijit Dutta, Himel Mondal, Tufan Khalua   +4 more
doaj   +1 more source

Predicting three-month fasting blood glucose and glycated hemoglobin changes in patients with type 2 diabetes mellitus based on multiple machine learning algorithms [PDF]

, 2023
Tao Xue, Min Jiang, Yumeng Liu, Qi Hu, Baoqiang Zhu, Jiaqiang Hu, Wenmei Guo, Xingwei Wu, Yu Xiong, Xia Shi, Xueli Zhang, Xu Han, Wenyuan Li, Rongsheng Tong, Enwu Long   +14 more
openalex   +1 more source