Results 61 to 70 of about 76,710 (335)

Comment on "Twisted Protein Aggregates and Disease: The Stability of Sickle Hemoglobin Fibers" [PDF]

open access: yesarXiv, 2010
Aggregates of twisted protein fibers, such as sickle hemoglobin and actin, are important examples of biopolymers in which elastic interactions play a crucial role in determining the (metastable) bundle radii. Here, we present a corrected version of analysis on the stability of sickle hemoglobin fibers using the classic nucleation theory.
arxiv  

Evidence of blood–brain barrier dysfunction and CSF immunoglobulin synthesis in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objectives This study sought to evaluate proteomic, metabolomic, and immune signatures in the cerebrospinal fluid of individuals with Down Syndrome Regression Disorder (DSRD). Methods A prospective case–control study comparing proteomic, metabolomic, and immune profiles in individuals with DSRD was performed.
Jonathan D. Santoro   +12 more
wiley   +1 more source

Localised IR spectroscopy of hemoglobin [PDF]

open access: yesarXiv, 2010
IR absorption spectroscopy of hemoglobin was performed using an IR optical parametric oscillator laser and a commercial atomic force microscope in a novel experimental arrangement based on the use of a bottom-up excitation alignment. This experimental approach enables detection of protein samples with a resolution that is much higher than that of ...
arxiv  

Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si   +7 more
wiley   +1 more source

Single-cell measurement of red blood cell oxygen affinity [PDF]

open access: yesarXiv, 2015
Oxygen is transported throughout the body by hemoglobin in red blood cells. While the oxygen affinity of blood is well understood and is routinely assessed in patients by pulse oximetry, variability at the single-cell level has not been previously measured.
arxiv  

Longitudinal Trajectories of Digital Cognitive Biomarkers for Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is one of the most common and debilitating symptoms of relapsing–remitting multiple sclerosis (RRMS). Digital cognitive biomarkers require less time and resources and are rapidly gaining popularity in clinical settings.
Yi Chao Foong   +17 more
wiley   +1 more source

Comparison of the effects of acute moderate-and high-intensity aerobic exercise on changes in hematological parameters and exercise-induced thrombocytosis in female college futsal players

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2018
Introduction and Aims: Type, intensity and duration of exercise, determining the effect of exercise on haematological indexes. The aim of this study was comparison of the effects of acute moderate-and high-intensity aerobic exercise on some hematological
abdossaleh zar, ,
doaj  

ron Intake in Adults from Medellin According to Demographics, 2012

open access: yesRevista Ciencias de la Salud, 2014
Objectives: To analyze the iron intake in healthy adults of Medellín according to demographics, and to determine the association between the consumption of iron and hemoglobin in this popula¬tion.
Carmen Yulieth Mantilla Gutiérrez   +1 more
doaj   +1 more source

Rapid point-of-care Hemoglobin measurement through low-cost optics and Convolutional Neural Network based validation [PDF]

open access: yesarXiv, 2017
A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin detectors which rely on micro cuvettes and dry chemistry. Any particulates (e.g.
arxiv  

Reconstitution of CXCR3+ CCR6+ Th17.1‐Like T Cells in Response to Ofatumumab Therapy in Patients With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang   +9 more
wiley   +1 more source

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