Results 171 to 180 of about 8,824 (214)
Some of the next articles are maybe not open access.
PAROXYSMAL COLD HEMOGLOBINURIAS
Archives of Internal Medicine, 1948DRESSLER 1 is credited with having first reported observations on a case of "paroxysmal cold hemoglobinuria," a symptom complex now known to have two separate and distinct etiologic bases. The first and more generally recognized type is syphilitic paroxysmal cold hemoglobinuria, a disease seen in a small percentage of persons with syphilis and caused ...
openaire +2 more sources
Paroxysmal Nocturnal Hemoglobinuria
Mayo Clinic ProceedingsParoxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired clonal hematologic disorder characterized by intravascular destruction of red blood cells by the complement system. This intravascular hemolysis can lead to a constellation of symptoms, including anemia, fatigue, shortness of breath, smooth muscle dystonia, and dark urine that is classically
Richard C. Godby, Surbhi Shah
openaire +2 more sources
Paroxysmal Cold Hemoglobinuria
CRC Critical Reviews in Clinical Laboratory Sciences, 1978The clinical and hematological features of a rare autoimmune disorder, PCH, are reviewed. Based on the case reports of 24 patients suffering from this disease, the presence of cold hemolysins in the sera of these patients as the main cause for the red cell destruction following exposure to cold is further discussed.
openaire +2 more sources
Paroxysmal nocturnal hemoglobinuria in pregnancy
Acta Obstetricia et Gynecologica Scandinavica, 2003Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic anemia in which a defect of glycophosphatidylinositol (GPI)‐anchored proteins in the cell membrane of bone marrow stem cells leads to increased sensitivity of the red cells to complement, causing intravascular hemolysis and hemoglobinuria.
Line, Bjørge +2 more
openaire +2 more sources
Thrombosis in paroxysmal nocturnal hemoglobinuria
Blood, 2013Abstract The most frequent and feared complication of paroxysmal nocturnal hemoglobinuria (PNH) is thrombosis. Recent research has demonstrated that the complement and coagulation systems are closely integrated with each influencing the activity of the other to the extent that thrombin itself has recently been shown to activate the ...
Anita, Hill +2 more
openaire +2 more sources
Paroxysmal Nocturnal Hemoglobinuria
1992Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal disorder of the hematopoietic stem cell (Hartmann and Arnold 1977) resulting in the production of blood cells which are defective in that they lack or are markedly deficient in glycan-phosphatidylinositol (GPI)-linked surface proteins (Rosse 1990a).
openaire +2 more sources
Paroxysmal Nocturnal Hemoglobinuria
Journal of Computer Assisted Tomography, 1993Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hemolytic disorder, characterized by hemosiderin deposition in the proximal renal tubules.We examined six cases of PNH with MRI including gradient echo imaging.On T2- and T2*-weighted imaging a characteristic hypointense pattern was noted in five of six patients with PNH.
Y O, Tanaka, I, Anno, Y, Itai, T, Abe
openaire +2 more sources
The syndrome of paroxysmal nocturnal hemoglobinuria
The American Journal of Medicine, 1964Abstract The case histories and investigations are presented of four patients with paroxysmal nocturnal hemoglobinuria who satisfy the diagnostic criteria of abnormal erythrocyte acid hemolysis, positive intravascular hemolysis and low erythrocyte acetylcholinesterase. The clinical presentations of these patients ranged from a young man with a classic
R W, BEAL, H, KRONENBERG, B G, FIRKIN
openaire +2 more sources
American Journal of Diseases of Children, 1933
It is well known that with some remedies, e. g., arsphenamine, mercury, bismuth and iodide of potassium, several years of continuous administration are required to ensure complete recovery from paroxysmal hemoglobinuria. Recently, S. Inamori of the department of pediatrics at Manchuria Medical College reported that the inoculation of Spirochaeta morsus-
openaire +1 more source
It is well known that with some remedies, e. g., arsphenamine, mercury, bismuth and iodide of potassium, several years of continuous administration are required to ensure complete recovery from paroxysmal hemoglobinuria. Recently, S. Inamori of the department of pediatrics at Manchuria Medical College reported that the inoculation of Spirochaeta morsus-
openaire +1 more source
Pregnancy and Paroxysmal Nocturnal Hemoglobinuria
Archives of Internal Medicine, 1988Our study concerns eight pregnancies, six of which were successful, in four patients with paroxysmal nocturnal hemoglobinuria (PNH). Several complications of PNH during pregnancy were prevented: chronic anemia, folate and iron deficiency, and deep-vein thrombosis.
P, Solal-Céligny +8 more
openaire +2 more sources