Results 111 to 120 of about 22,402 (256)

Intoxicação espontânea e experimental por Brachiaria radicans (tanner-grass) em bovinos Natural and experimental poisoning by Brachiaria radicans (tanner grass) in cattle

open access: yesPesquisa Veterinária Brasileira, 2010
Brachiaria radicans (tanner-grass,) cresce bem em solos úmidos. Em Santa Catarina é encontrada principalmente nas regiões dos vales dos rios Tubarão e Itajaí.
Aldo Gava   +4 more
doaj   +1 more source

Paroxysmal nocturnal hemoglobinuria

open access: yesCurrent Opinion in Hematology, 2012
The aim is to report on recent observations related to the natural history of paroxysmal nocturnal hemoglobinuria (PNH) and to review new therapeutic strategies for controlling the hemolysis of PNH.This review focuses on studies designed to characterize the long-term outcome of patients with PNH treated with eculizumab and to define the relationship ...
openaire   +6 more sources

Paroxysmal Nocturnal Hemoglobinuria [PDF]

open access: yesBlood, 1950
Abstract 1. Paroxysmal noctural hemoglobinuria is believed to be an acquired disease of the hematopoietic system in which abnormal red cells, white cells, and platelets are produced. The lesion of the cells probably involves the stromal proteins in such a fashion that they are susceptible to the proteolytic effect of a sytem of normal ...
openaire   +2 more sources

Comparison of four different in vitro assays for prediction of potential RBC antibody clinical significance

open access: yesTransfusion, Volume 66, Issue 9, Page 1830-1839, September 2026.
Abstract Background The monocyte monolayer assay (MMA) uses monocytes, but it is known that antibody‐mediated hemolysis occurs in macrophages. Whether the use of macrophages would improve the predictive capacity of the MMA is unclear. Also, it is unclear if RBC alloantibodies contribute to hemolysis via antibody‐dependent cellular cytotoxicity (ADCC ...
Yeniley Ruiz Noa   +6 more
wiley   +1 more source

Pregnancy in Classical Paroxysmal Nocturnal Hemoglobinuria and Aplastic Anemia–Paroxysmal Nocturnal Hemoglobinuria: A High-Risk Constellation

open access: yesFrontiers in Medicine, 2020
Pregnancies in paroxysmal nocturnal hemoglobinuria (PNH) are associated with increased morbidity and mortality. Retrospective studies suggest that outcome has improved with the advent of the complement inhibitor eculizumab.
F. Alashkar   +7 more
semanticscholar   +1 more source

Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents

open access: yes, 2008
Antonio M Risitano, Bruno RotoliHematology, Department of Biochemistry and Medical Biotechnologies, Federico II University of Naples, ItalyAbstract: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal non-malignant hematological disease characterized ...
RISITANO, ANTONIO MARIA   +3 more
core  

Paroxysmal nocturnal hemoglobinuria [PDF]

open access: yesVnitřní lékařství, 2018
Paroxysmal nocturnal hemoglobinuria (PNH) results from a deficiency in inhibitors of activated complement. This lack leads to complement mediated intravascular hemolysis, to activation of coagulation system with increased risk of thrombotic complications and to various degree of bone marrow failure.
openaire   +2 more sources

Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm

open access: yes, 2016
Yarden S Fraiman,1,2 Nathan Cuka,3 Denise Batista,3 Milena Vuica-Ross,3 Alison R Moliterno4 1Department of Pediatrics, Harvard Medical School, 2Department of Pediatrics, Boston University School of Medicine, Boston, MA, 3Department of Pathology ...
Cuka N   +4 more
core  

Evans' syndrome in paroxysmal nocturnal hemoglobinuria.

open access: yes, 1985
We describe the first case of paroxysmal nocturnal hemoglobinuria with Evans' syndrome. The immunohematological studies of this patient, a 27-year-old man, revealed the presence of red cell and platelet autoantibodies, related to an episode of anemia and
GIRELLI, Gabriella   +3 more
core   +1 more source

Frequency of Paroxysmal Nocturnal Hemoglobinuria Clone in Turkish Myelodysplastic Syndrome Group [PDF]

open access: yes, 2018
Aim:Retrospective, cross-sectional, observational study to examine the frequency and features of paroxysmal nocturnal hemoglobinuria (PNH) clones in patients with myelodysplastic syndrome (MDS).Methods:Data were analyzed from the medical files of 41 MDS ...
Mesut Ayer   +6 more
core   +1 more source

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