Results 101 to 110 of about 22,402 (256)

PAROXYSMAL HEMOGLOBINURIA [PDF]

Journal of the American Medical Association, 1914
History. —J., a man aged 45, Swedish, a sheet-metal worker, entered the Peter Bent Brigham Hospital, Sept. 11, 1913, complaining of chills, fever and bloody urine. The family history was unimportant as related to the present illness. The patient had interstitial keratitis at 3 years (?), and measles and small-pox as a child, but no other infectious ...
openaire   +2 more sources

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

High Proportion of PNH Type II Neutrophils Is Associated With Thrombosis in Patients Displaying a PNH Clone ≥ 1%

American Journal of Hematology, Volume 101, Issue 9, Page 2311-2328, September 2026.
ABSTRACT The clinical significance of PNH Type II white blood cells (WBCs) remains unclear. We assessed the relative percentage (rel%) of Type II neutrophils in 355 patients with a PNH clone ≥ 1% on neutrophils enrolled by 33 flow cytometry laboratories in the 5‐year French nation‐wide multicenter prospective observational study.
Orianne Wagner‐Ballon, Anne‐Catherine Lhoumeau, Anna Raimbault, Camille Debord, Jean‐Philippe Vial, Valérie Soenen, Mélanie Pannetier, Edouard Bonneville, Elsa Bera, Caroline Bret, Nicolas Chapuis, Véronique Latger‐Cannard, Caroline Mayeur‐Rousse, Véronique Harrivel, François Vergez, Marie Loosveld, Juliette Vo Xuan, Stéphanie Mathis, Gérard Socié, Flore Sicre de Fontbrune, Régis Peffault de Latour, Bernard Drenou, Agathe Debliquis, Magali Le Garff‐Tavernier, on behalf of the French PNH working group CytHem‐HPN, Thomas Boyer, Mikaël Roussel, Marie Guillon, Sabrina Bouyer, Isabelle Kittler, Franck Geneviève, Julien Guy, Sophie Brun, Claude Capron, Sébastien Lachot, Francine Garnache‐Ottou, Richard Veyrat‐Masson, Corine Brunet, Caren Brumpt, Ludovic Lhermitte. Finally, Louis Terriou, Nicolas Blin   +41 more
wiley   +1 more source

Paroxysmal nocturnal hemoglobinuria: patient journey and burden of disease

Journal of Managed Care & Specialty Pharmacy, 2020
Patients with paroxysmal nocturnal hemoglobinuria (PNH) often experience a lengthy path to diagnosis. Fewer than 40% of patients with PNH receive a diagnosis within 12 months of symptom onset, and 24% of all PNH diagnoses can take 5 years or longer ...
M. Bektas, C. Copley-Merriman, Shahnaz Khan, S. Sarda, J. Shammo   +4 more
semanticscholar   +1 more source

Intoxicação crônica por cobre em ovinos: conduta para o diagnóstico conclusivo Chronic copper toxicities in sheep: conduct for diagnostic confirmation

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Descreveram-se os sinais clínicos e achados anatomopatológicos da intoxicação crônica por cobre em um ovino da raça Texxel e definiu-se a conduta diagnóstica correta para confirmação da enfermidade.
M.P. Miguel, M.A. Souza, P.H.J. Cunha, G.L. Costa, L.J. Abud   +4 more
doaj  

Clinical Case and Follow‐Up of Babesia banethi Infection in a Red Fox

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
A naturally occurring Babesia banethi infection in a sick red fox was followed up for more than one year through cytology, haematobiochemical profiles and molecular analyses. Imidocarb treatment resulted in temporary clinical improvement and later relapse, whereas atovaquone/proguanil combined with azithromycin led to clinical recovery and parasite ...
Mariaelisa Carbonara, Michela Prioletti, Antonio Camarda, Stefano Castellana, Giuseppe Menga, Giovanna Girardi, Gad Baneth, Domenico Otranto   +7 more
wiley   +1 more source

The pathophysiology of paroxysmal nocturnal hemoglobinuria and treatment with eculizumab

, 2009
Richard Kelly1, Stephen Richards1, Peter Hillmen1, Anita Hill21Institute of Oncology, St. James’s University Hospital, Leeds, UK; 2Department of Haematology, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UKAbstract: Paroxysmal ...
Stephen Richards, Peter Hillmen, et al, Richard Kelly   +3 more
core  

What Is Your Diagnosis? Severe Anemia in an Adult Alpaca

Veterinary Clinical Pathology, EarlyView.
Brittany N. Martin, Ji Ann Greenberg, Pabasara Weerarathne, Guilherme Verocai, Dusty W. Nagy, Mary B. Nabity, Mark C. Johnson   +6 more
wiley   +1 more source

Clinically Important Emerging and Uncommon Fungal Pathogens in Asia: Epidemiology, Antifungal Resistance and Challenges in Diagnosis and Management

Mycoses, Volume 69, Issue 9, September 2026.
ABSTRACT Fungal infections in Asia are influenced by warm, humid climates, high population density and expanding healthcare systems, which together facilitate the emergence, transmission and detection of both common and rare pathogens. While Candida and Aspergillus species remain the leading causes of invasive fungal disease, increasing attention has ...
Narut Chancharussin, Anupop Jitmuang, Arunaloke Chakrabarti, Methee Chayakulkeeree   +3 more
wiley   +1 more source

Cost-Utility Analysis of Ravulizumab Compared with Eculizumab in Adult Patients with Paroxysmal Nocturnal Hemoglobinuria

PharmacoEconomics (Auckland), 2020
Background Paroxysmal nocturnal hemoglobinuria, characterized by intravascular hemolysis and venous thrombosis, can be managed with eculizumab, an inhibitor of the complement system; however, patients may periodically experience breakthrough hemolysis ...
Thomas O’Connell, M. Buessing, Scott J Johnson, L. Tu, Simu K. Thomas, I. Tomazos   +5 more
semanticscholar   +1 more source