Results 91 to 100 of about 13,040 (222)

Randomised, phase 1 evaluation of the safety, tolerability, pharmacokinetics and pharmacodynamics of iptacopan in healthy volunteers

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2874-2889, June 2026.
Abstract Background and Purpose Overactivation of the alternative pathway (AP) underlies several diseases. Iptacopan is an oral, first‐in‐class, highly potent specific inhibitor of factor B, a key AP protease. Experimental Approach The analysis included data from two phase 1 randomised, volunteer‐blinded, placebo‐controlled studies: Study 1, a single ...
Irina Baltcheva   +5 more
wiley   +1 more source

Bovine postparturient hemoglobinuria

open access: yes, 1982
Predisposing causes of bovine post-parturient hemoglobinuria are summarized along with suspected pathogeneses, clinical signs, laboratory findings, clinical management and early experimentation.PUBM: Print; JID: 0004653; ppublishSource type: Electronic ...

core  

Naphthalene poisoning manifesting as hemoglobinuria

open access: yesToxicology International, 2014
Reddish black discoloration of urine in absence of red blood cells (RBCs) can be a manifestation of hemoglobinuria or myoglobinuria. We report a patient who was admitted for persistent vomiting. On 2(nd) day of admission, his urine turned reddish black. The patient then revealed that he had ingested mothballs 1 day back to commit suicide.
Chauhan, Vivek   +5 more
openaire   +3 more sources

Importancia del diagnóstico de Hemoglobinuria Paroxística nocturna como manejo de anemia aplásica con población celular hemática deficientes de gpi: revisión literaria

open access: yes, 2020
En primera instancia, este trabajo de grado se basa en expresar la importancia en el diagnóstico de HPN en personas que presenten anemia aplásica mediante la búsqueda en bases de datos sobre referencias documentales que demuestren bases teóricas sobre ...
Castro Córdoba, Daniela Alexandra
core   +1 more source

PAROXYSMAL HEMOGLOBINURIA [PDF]

open access: yesArchives of Internal Medicine, 1910
In the case presented in this article, on which our work was performed, any severe chilling of the patient's skin caused a temporary hemoglobinuria, drowsiness, regurgitation of food and other minor symptoms to be mentioned later. The phenomena were produced either by a chilling of the general body surface or, what was more common, by the mere exposure
openaire   +1 more source

Adult TWIST2‐high B‐ALL confirms metabolic association but reveals molecular heterogeneity

open access: yes
HemaSphere, Volume 10, Issue 6, June 2026.
Wencke Walter   +3 more
wiley   +1 more source

Paroxismal cold hemoglobinuria: when to suspect? [PDF]

open access: yes, 2012
RESUMO Introdução: A hemoglobinúria paroxística ao frio é uma forma rara de apresentação de anemia hemolítica auto-imune. Caso Clínico: Descreve-se o caso de uma criança, de 23 meses de idade, com icterícia e urina escura de início súbito.
Lira, S.   +4 more
core  

Paroxysmal Nocturnal Hemoglobinuria and Acute Kidney Injury: A Case Report

open access: yes, 2013
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare cause of hemolytic anemia. The major outlines of clinical presentation comprises findings of hemolysis, venous thrombosis and findings of bone marrow failure.
Rumeyza Kazancioglu   +13 more
core   +1 more source

Hemoglobinuria paroxística nocturna

open access: yes, 1994
It is presented a review of the pathophysiology, diagnostic, differential diagnostic, clinical aspects and therapeutic approach of the patients with the diagnostic of nocturnal paroxysmal hemoglobinuria.Se presenta una revisión de la fisiopatología ...
Uribe Arango, William
core  

Problems of diagnosing paroxism night hemoglobinuria in Ukraine

open access: yes, 2019
Problems of diagnosing paroxism night hemoglobinuria in ...
Kovalova, Ksenia   +2 more
core  

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