Results 171 to 180 of about 13,040 (222)

Paroxysmal Nocturnal Hemoglobinuria in Children

Pediatric Drugs, 2007
Paroxysmal nocturnal hemoglobinuria (PNH), an acquired hematologic disorder characterized by intravascular hemolysis, nocturnal hemoglobinuria, thrombotic events, serious infections, and bone marrow failure, is very rare in children. PNH is caused by a somatic mutation of the phosphatidylinositol glycan (GPI) complementation class A (PIGA) gene ...
Heuvel-Eibrink, M.M. (Marry) van den, Van den Heuvel - Eibrink, Marry   +1 more
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Hemoglobinemia and the Hemoglobinurias

New England Journal of Medicine, 1945
BLACKWATER, or more scientifically, hemoglobinuria, attracts the attention of patient and physician as do few other symptoms.
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Paroxysmal Cold Hemoglobinuria

Hematology/Oncology Clinics of North America, 2015
Paroxysmal cold hemoglobinuria is a rare cause of autoimmune hemolytic anemia predominantly seen as an acute form in young children after viral illnesses and in a chronic form in some hematological malignancies and tertiary syphilis. It is a complement mediated intravascular hemolytic anemia associated with a biphasic antibody against the P antigen on ...
Satish, Shanbhag, Jerry, Spivak
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Hemoglobinuria With Ribavirin Treatment

Journal of Clinical Gastroenterology, 2003
Chronic hepatitis C virus is a major worldwide cause of hepatitis, cirrhosis, end-stage liver disease, and hepatocellular carcinomas. Combination therapy of ribavirin with short- or long-acting interferon-alpha is now the standard treatment of chronic hepatitis C. This therapy is associated with a wide range of side effects.
Omar I, Massoud, Wael I, Yousef, Kevin D, Mullen   +2 more
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Hemolytic Anemia with Hemoglobinuria

American Journal of Clinical Pathology, 1948
Hemolytic anemia with hemoglobinuria is frequently a striking clinical event indicative of extensive intravascular hemolysis. The condition lends itself to detailed study because of the morphologic abnormalities in the blood and bone marrow, the marked accumulation of hemoglobin and its derivatives in the blood plasma and urine, the aberrations of ...
D, STATS, L R, WASSERMAN, N, ROSENTHAL
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Paroxysmal nocturnal hemoglobinuria

Hématologie, 2013
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disorder of hematopoietic stem cells. PNH is related to a somatic mutation in the phosphatidylinositol glycan class A (PIG-A), X-linked gene, responsible for a deficiency in glycosylphosphatidylinositol-anchored proteins (GPI-AP).
R, Peffault de Latour, Z, Amoura, G, Socié   +2 more
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March Hemoglobinuria in a Woman

New England Journal of Medicine, 1950
THE literature now contains many reports of cases of "march hemoglobinuria" in men,1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 but to date there has been only one report of this condition occurring in a woman.14 The diagnosis of march hemoglobinuria is made in subjects in whom marching, walking or running occasions the passage of red urine containing ...
D R, GILLIGAN, M D, ALTSCHULE
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Paroxysmal Nocturnal Hemoglobinuria

Mayo Clinic Proceedings
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired clonal hematologic disorder characterized by intravascular destruction of red blood cells by the complement system. This intravascular hemolysis can lead to a constellation of symptoms, including anemia, fatigue, shortness of breath, smooth muscle dystonia, and dark urine that is classically
Richard C. Godby, Surbhi Shah
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