Results 91 to 100 of about 89,871 (313)
CPL‐Diff: A Diffusion Model for De Novo Design of Functional Peptide Sequences with Fixed Length
Advanced Science, EarlyView.This study presents a diffusion model for generating functional peptide sequence lengths using mask control. The model can generate antimicrobial, antifungal, and antiviral peptides with specific lengths on demand. The model learns the structure of peptides better and generates peptides with better physicochemical properties, and the model has good ...
Zhenjie Luo +5 more
wiley +1 more source
Toxins, 2016 Despite the medical urgency presented by cubozoan envenomations, ineffective and contradictory first-aid management recommendations persist. A critical barrier to progress has been the lack of readily available and reproducible envenomation assays that ...
Angel A. Yanagihara +4 more
doaj +1 more source
Observations on the Anemia of Cryptogenetic Splenomegaly. I. Hemolysis [PDF]
, 1958 A. J. S. McFadzean, D. Todd, K. C. TSANG
openalex +1 more source
Experimental Biology and Medicine, 1906 There are several reasons suggesting that a hemolytic agent of placental origin may be of essential importance in eclampsia. The occurrence of methemoglobinuria, the possible relation of the hepatic thromboses to hemolyzed red cells, the resemblance between the eclamptic lesions and those produced by the injection of eclamptic serum or of immune ...
openaire +2 more sources
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
Advanced Science, EarlyView.In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa +5 more
wiley +1 more source
Bringing Packed Red Blood Cells to the Point of Combat Injury: Are We There Yet?
Turkish Journal of Hematology, 2018 Objective: Hemorrhage is the leading cause of injury-related prehospital mortality. We investigated worst-case scenarios and possible requirements of the Turkish military.
Aytekin Ünlü +11 more
doaj +1 more source
Towards Robust Hemolysis Modeling with Uncertainty Quantification: A Universal Approach to Address Experimental Variance [PDF]
arXivPurpose: The purpose of this study is to address the lack of uncertainty quantification in numerical hemolysis models, which are critical for medical device evaluations. Specifically, we aim to incorporate experimental variability into these models using the Markov Chain Monte Carlo (MCMC) method to enhance predictive accuracy and robustness. Methods:
arxiv
Advanced Science, EarlyView.The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li +11 more
wiley +1 more source