Results 91 to 100 of about 206,019 (383)

A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations [PDF]

, 2019
Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling.
Ayguasanosa, J, Balasa, R, Bril, V, Camprubi, S, Chen, J, De Bleecker, Jan, Garcia, B, Griffin, R, Heckmann, JM, Henriquez, W, Karelis, G, Lagrange, E, Mondou, E, Nicolle, M, Stuchevskaya, T, Van Damme, P, Vilciu, C, Villa, A   +17 more
core   +2 more sources

A lipolytic form of hemolysis [PDF]

Experimental Biology and Medicine, 1906
The varieties of hemolysis hitherto described imply the direct action of certain chemically-defined bodies, acids, alkalis, glucosides, — which attack and destroy the integrity of the red corpuscles, and other chemically undefined bodies, — bacterial hemolysins, which act in the same manner, and the more indirect action of certain complexes defined as ...
openaire   +3 more sources

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Pediatric hemolysis in emergency departments: Prevalence, risk factors, and clinical implications.

PLoS ONE
ObjectiveThis study aimed to analyze the prevalence, risk factors, and clinical implications of hemolyzed laboratory samples in the pediatric emergency department (ED), a subject on which existing data remains scarce.MethodsWe conducted a multi-site ...
Nicholas Mielke, Ray Lee, Amit Bahl
doaj   +1 more source

An in vitro method to evaluate hemolysis of human red blood cells (RBCs) treated by airborne particulate matter (PM10)

MethodsX, 2019
Air pollutants are capable to enter bloodstream through the nose, mouth, skin and the digestive tract. Hemolysis is the premature destruction of red blood cells (RBCs) membranes. This can affect metabolism of RBCs and reduce cell life.
Alireza Mesdaghinia, Zahra Pourpak, Kazem Naddafi, Ramin Nabizadeh Nodehi, Zahra Alizadeh, Soheila Rezaei, Amir Mohammadi, Maryam Faraji   +7 more
doaj   +1 more source

Influence of estimated training status on anti and pro-oxidant activity, nitrite concentration, and blood pressure in middle-aged and older women [PDF]

, 2017
The purpose of this study was to compare the association between anti and pro-oxidant activity, nitrite concentration, and blood pressure (BP) in middle-aged and older women with different levels of estimated training status (TS). The sample consisted of
Amaral, Sandra L., Brito, Janaina de Oliveira, da Silva, Roberta F., De Angelis, Kátia, Dias, Danielle da Silva, Jacomini, André M., Llesuy, Susana Francisca, Monteiro, Henrique L., Zago, Anderson S.   +8 more
core   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Characterization of Protein Involved in Hemolysis Expressed by Sneathia amnii, a Pathogen of the Female Urogenital Tract [PDF]

, 2019
Sneathia amnii is a poorly characterized gram-negative anaerobe that commonly colonizes the vagina. It has been linked to many obstetric disorders, including preterm labor, preeclampsia, and chorioamnionitis. S.
Carrasco, Lizette, Gentile, Gabriella, Jefferson, Kimberly, Stanford, Amy   +3 more
core   +1 more source

Toxin-neutralizing antibodies protect against Clostridium perfringens-induced necrosis in an intestinal loop model for bovine necrohemorrhagic enteritis [PDF]

, 2016
Background: Bovine necrohemorrhagic enteritis is caused by Clostridium perfringens type A. Due to the rapid progress and fatal outcome of the disease, vaccination would be of high value. In this study, C.
Deprez, Piet, Ducatelle, Richard, Goossens, Evy, Haesebrouck, Freddy, Pardon, Bart, Rodrigo, Diego, Schauvliege, Stijn, Timbermont, Leen, Valgaeren, Bonnie, Van Immerseel, Filip, Verherstraeten, Stefanie   +10 more
core   +2 more sources

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source