Clinical aspects of a nationwide epidemic of severe haemolytic uremic syndrome (HUS) in children [PDF]
Background Report a nationwide epidemic of Shiga toxin-producing E. coli (STEC) O103:H25 causing hemolytic uremic syndrome (D+HUS) in children.
Krogvold, Lars +8 more
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Atypical haemolytic-uraemic syndrome caused by factor H mutation: case report and new management strategies in children [PDF]
Atypical haemolytic uraemic syndrome is causedby alternative complement pathway dysregulation. It has recently been recognised that most cases are due to genetic factors and a growing list of mutations has been described.
Araújo, L. +5 more
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Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: a case report [PDF]
INTRODUCTION: Thrombotic microangiopathies are a group of diseases presenting as microangiopathic hemolytic anemia, thrombocytopenia and end-organ dysfunction.
Abdulkadir Unsal +11 more
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Maro Ohanian, Christian Cable, Kathleen HalkaDepartment of Hematology and Oncology, Scott and White Healthcare, The Texas A&M Health Science Center College of Medicine, Temple, TX, USAAbstract: This case report describes how eculizumab reversed ...
Ohanian M, Cable CC, Halka KK
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Eculizumab experience in an adult patient with atypical hemolytic uremic syndrome
Atypical hemolytic-uremic syndrome is a disease characterized by nonimmune hemolytic anemia, thrombocytopenia, and renal failure. In this study, we present a case of a patient with atypical hemolytic-uremic syndrome treated successfully with eculizumab ...
Funda Sari +6 more
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Humoral immune response to Shiga Toxin 2 (Stx2) among Brazilian urban children with hemolytic uremic syndrome and healthy controls [PDF]
Background: Shiga toxin (Stx)-producing Escherichia coli (STEC) infection is associated with hemolytic uremic syndrome (HUS), the main cause of acute renal failure in early childhood.
Guirro, Mirian +3 more
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The article presents information about Escherichia coli infections, the outbreak of which was recorded in 2011 in Europe. In Hrodno region for 15 years of observations, there were registered 158 cases of Escherichia coli infection, the proportion of ...
N.V. Pronko +2 more
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Clinical case of thrombotic microangiopathy in obstetric practice
Trombotic microangiopathy is heterogeneous group of the diseases united by a community of a histological and clinical implications at difference of pathogenetic mechanisms, presents clinical-morphological syndrome characterizing a lesion of vessels of a ...
M. N. Mochalova +5 more
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Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies
Lindsay S Keir,1 Stephen D Marks,2 Jon Jin Kim21Academic Renal Unit, University of Bristol, Bristol; 2Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United KingdomAbstract: Hemolytic uremic syndrome is the
Keir LS, Marks SD, Kim JJ
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MALIGNANT ARTERIAL HYPERTENSION IN A CHILD WITH ATYPICAL HEMOLYTIC-UREMIC SYNDROME
Atypical hemolytic-uremic syndrome (aHUS) is a rare orphan disease. In the Altai Region, two cases of aHUS among children have been recorded. The disease is characterized by a severe course with high mortality, frequent development of complications and a
Олеся Алексеевна Зенченко +5 more
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