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C3 molecular structural and histopathological analyses in a pediatric case of atypical hemolytic uremic syndrome with life-threatening gastrointestinal bleeding-a case report. [PDF]

open access: yesFront Pediatr
Enya T   +12 more
europepmc   +1 more source

The Hemolytic Uremic Syndrome

Pediatric Clinics of North America, 1976
It is becoming increasingly apparent that the hemolytic uremic syndrome is a heterogenic and heterogeneous syndrome. There has been a dramatic reduction in the number of patients who die in the acute phase of the illness. Any claims for the use of heparin and streptokinase must be measured against the improved results which are now being obtained with ...
B S, Kaplan   +2 more
openaire   +2 more sources

The Hemolytic-Uremic Syndrome

Nephron, 2008
The clinical and pathological characteristics of the acute stage of the HUS are described on the basis of 678 patients and the study of 52 autopsies and 3 kidney biopsies. The laboratory and pathological studies point to DIC as a basic pathogenic mechanism, probably related to a viral infection.
C A, Gianantonio   +4 more
openaire   +2 more sources

Hemolytic Uremic Syndrome

Postgraduate Medicine, 1965
It is suggested that the hemolytic uremic syndrome is common to a number of morbid conditions and is not a new entity. Three illustrative cases are presented, all of them fatal. Necropsy revealed diverse pathologic processes (microangiopathic hemolytic anemia, acute glomerulonephritis with pyelonephritis, malignant hypertension).
S, SUSSMAN, S, FRENCH
openaire   +4 more sources

Hemolytic-uremic syndrome

The Indian Journal of Pediatrics, 1984
There have been major advances in the understanding of pathogenesis and management of hemolytic uremic syndrome in the last decade. Since the consensus paper published in 2009 by the European Pediatric Study Group in 2009, there have been four prospective trials and multiple case reports on effective terminal blockade with Eculizumab, an international ...
A K, Shah, K R, Sheth
openaire   +2 more sources

Hemolytic Uremic Syndrome

Pediatrics in Review, 2020
1. Bernarda Viteri, MD* 2. Jeffrey M. Saland, MD† 1. *Children’s Hospital of Philadelphia, Philadelphia, PA 2. †Mount Sinai Kravis Children’s Hospital, New York, NY Thrombotic microangiopathy (TMA) was described by Moschcowitz in 1924, and the term hemolytic uremic syndrome (HUS) appeared by 1955 to describe a series of patients with small ...
Bernarda, Viteri, Jeffrey M, Saland
openaire   +2 more sources

The hemolytic uremic syndromes

Current Opinion in Critical Care, 2005
Recent studies have provided a better understanding of the molecular mechanisms responsible for hemolytic uremic syndromes. In this review, we summarize biochemical and genetic data that may lead to new clinical approaches.The structures and modes of action of Shiga toxins have been deciphered.
Jessica, Caprioli   +2 more
openaire   +2 more sources

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