Impact of the Hydrolysis and Methanolysis of Bidesmosidic Chenopodium quinoa Saponins on Their Hemolytic Activity [PDF]
Molecules, 2022 Saponins are specific metabolites abundantly present in plants and several marine animals. Their high cytotoxicity is associated with their membranolytic properties, i.e., their propensity to disrupt cell membranes upon incorporation.
Philippe Savarino +5 more
doaj +2 more sources
Bacillus velezensis iturins inhibit the hemolytic activity of Staphylococcus aureus [PDF]
Scientific ReportsBovine mastitis caused by S. aureus has a major economic impact on the dairy sector. With the crucial need for new therapies, anti-virulence strategies have gained attention as alternatives to antibiotics.
Yasmin Neves Vieira Sabino +9 more
doaj +2 more sources
Hemolytic activity of venom from crown-of-thorns starfish Acanthaster planci spines
Journal of Venomous Animals and Toxins including Tropical Diseases, 2013 Background : The crown-of-thorns starfish Acanthaster planci is a venomous species from Taiwan whose venom provokes strong hemolytic activity. To understand the hemolytic properties of A. planci venom, samples were collected from A.
Chi-Chiu Lee +3 more
doaj +2 more sources
Comparison of the hemolytic activity between C. albicans and non-albicans Candida species [PDF]
Brazilian Oral Research, 2013 The ability to produce enzymes, such as hemolysins, is an important virulence factor for the genus Candida.The objective of this study was to compare the hemolytic activity between C. albicansand non-albicans Candida species.
Rodnei Dennis Rossoni +4 more
openalex +2 more sources
Prediction of hemolytic peptides and their hemolytic concentration
Communications BiologyPeptide-based drugs often fail in clinical trials due to their toxicity or hemolytic activity against red blood cells (RBCs). Existing methods predict hemolytic peptides but not the concentration (HC50) required to lyse 50% of RBCs.
Anand Singh Rathore +4 more
doaj +2 more sources
Antibacterial and Hemolytic Activity of Crotalus triseriatus and Crotalus ravus Venom [PDF]
Animals, 2020 Rattlesnakes have venoms with a complex toxin mixture comprised of polypeptides and proteins. Previous studies have shown that some of these polypeptides are of high value for the development of new medical treatments.
Adrian Zaragoza-Bastida +8 more
doaj +2 more sources
Cationicity Enhancement on the Hydrophilic Face of Ctriporin Significantly Reduces Its Hemolytic Activity and Improves the Antimicrobial Activity against Antibiotic-Resistant ESKAPE Pathogens [PDF]
ToxinsThe ESKAPE pathogen-associated antimicrobial resistance is a global public health issue, and novel therapeutic strategies are urgently needed. The short cationic antimicrobial peptide (AMP) family represents an important subfamily of scorpion-derived ...
Xudong Luo +6 more
doaj +2 more sources
Journal of Biological ResearchHemolytic activity assessment is a widely used method to evaluate the toxicity of marine organisms, including jellyfish. However, there are some challenges associated with testing hemolytic activity.
Yongfang Wang +7 more
doaj +3 more sources
Orally administered β-glucan improves the hemolytic activity of the complement system in horses. [PDF]
Vet World, 2021 Picetti TS +7 more
europepmc +3 more sources