Results 11 to 20 of about 1,173,760 (131)

Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies

Drug Design, Development and Therapy, 2012
Lindsay S Keir,1 Stephen D Marks,2 Jon Jin Kim21Academic Renal Unit, University of Bristol, Bristol; 2Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United KingdomAbstract: Hemolytic uremic syndrome is the
Keir LS, Marks SD, Kim JJ
doaj   +1 more source

Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]

, 2010
Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Douglas, Kenneth W., Pollock, Kevin G.J., Catlow, Jamie, Young, David, Green, Rachel   +4 more
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Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]

, 2008
The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
Todd, W.T.A., Beattie, T.J., Pollock, K.G.J., Young, D.   +3 more
core   +4 more sources

Nephrotic syndrome associated with primary atypical hemolytic uremic syndrome

Brazilian Journal of Nephrology, 2020
Primary atypical hemolytic-uremic syndrome is a rare disease characterized by non-immune microangiopathic hemolytic anemia, thrombocytopenia, and renal dysfunction; it is related to alterations in the regulation of the alternative pathway of complement ...
Diana Carolina Bello-Marquez, John Fredy Nieto-Rios, Lina Maria Serna-Higuita, Alfonso Jose Gonzalez-Vergara   +3 more
doaj   +2 more sources

Attack of the clones: whole genome-based characterization of two closely related enterohemorrhagic Escherichia coli O26 epidemic lineages

BMC Genomics, 2018
Background Enterohemorrhagic Escherichia coli (EHEC) O26:H11/H−, the most common non-O157 serotype causing hemolytic uremic syndrome worldwide, are evolutionarily highly dynamic with new pathogenic clones emerging rapidly.
Lucia Karnisova, Monika Marejkova, Hana Hrbackova, Alexander Mellmann, Helge Karch, Angelika Fruth, Pavel Drevinek, Kveta Blahova, Martina Bielaszewska, Jaroslav Nunvar   +9 more
doaj   +1 more source

Atypical hemolytic uremic syndrome: a case report

Journal of Medical Case Reports, 2020
Background Thrombotic microangiopathy is a pathological condition comprised of microvascular thrombosis involving any organ of the body leading to thrombocytopenia, Coombs-negative hemolytic anemia, and end-organ damage.
B. M. D. B. Basnayake, A. W. M. Wazil, N. Nanayakkara, S. M. D. K. Samarakoon, E. M. S. K. Senavirathne, B. U. E. W. D. R. Thangarajah, N. Karunasena, R. M. B. S. S. Mahanama   +7 more
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Neurological involvement and MRI brain findings in an adult with hemolytic uremic syndrome: A case report

Radiology Case Reports, 2020
Hemolytic uremic syndrome is a frequent complication of shiga toxin producing Escherichia coli in pediatric population. It rarely affects adults with extremely rare neurological manifestation.
A. Abdelrahman, MD, A. Nada, MD, PhD, E. Park, A. Humera, MD   +3 more
doaj   +1 more source

Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United Kingdom [PDF]

, 2010
Atypical haemolytic uraemic syndrome (aHUS) is associated with a poor prognosis with regard to survival at presentation, recovery of renal function and transplantation.
Sam Machin, ?, ?, Machin, Sam, Tim H. J. Goodship, Goodship, Tim H J, Stephen J. Wigmore, Taylor, C Mark, Wigmore, Stephen J, C. Mark Taylor   +8 more
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Thrombotic Thrombocytopenic Purpura, Moschcowitz Syndrome [PDF]

, 2001
The authors present a case of a 16-year-old boy, who was referred to the hospital due to thrombocytopenia, anemia, proteinuria and hyperbilirubinemia. Based on the clinical picture and the laboratory data, thrombotic thrombocytopenic purpura (TTP) was ...
Czinyéri, Judit, Sasvári, Ildikó, Kovács, Gábor, Garami, Miklós, Müller, Judit   +4 more
core   +1 more source

Pathogenic Potential to Humans of Bovine Escherichia coli O26, Scotland [PDF]

, 2012
Escherichia coli O26 and O157 have similar overall prevalences in cattle in Scotland, but in humans, Shiga toxin–producing E. coli O26 infections are fewer and clinically less severe than E. coli O157 infections.
Low, JC, Mary F. Hanson, Matthews, L., Alfredo Caprioli, Pollock, K.J., J. Chris Low, Chase-Topping, ME, Caprioli, A, Chase-Topping, M.E., Pearce, M.C., Evans, J., Allison, L.J., Matthews, L, Emily Courcier, Pearce, MC; id_orcid, Michael C. Pearce, David L. Gally, Judith Evans, Courcier, E, Caprioli, A., Locking, M.E., Woolhouse, M.E.J., Allison, LJ, Rosser, T., Handel, I., Louise Matthews, Iain J. McKendrick, Helge Karch, Rosser, T, Gally, DL, Margo E. Chase-Topping, Courcier, E., Tracy Rosser, Gally, D.L., McKendrick, IJ, Evans, J, Karch, H., Hanson, MF, Hanson, Mary, Lesley J. Allison, Low, J.C., Pollock, KGJ, Woolhouse, M.E.; id_orcid, Hanson, M.F., Woolhouse, MEJ, Ian Handel, Pollock, K.G., Mary E. Locking, Karch, H, Kevin G.J. Pollock, Locking, ME, Mark E.J. Woolhouse, Handel, I, McKendrick, I.J.   +53 more
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