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The role of matrix metalloproteinase 9 in immune-mediated skin diseases. [PDF]
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Revisiting the interaction of heme with hemopexin
Biological Chemistry, 2021Abstract In hemolytic disorders, erythrocyte lysis results in massive release of hemoglobin and, subsequently, toxic heme. Hemopexin is the major protective factor against heme toxicity in human blood and currently considered for therapeutic use. It has been widely accepted that hemopexin binds heme with extraordinarily high affinity of &
Benjamin Franz Schmalohr +2 more
exaly +3 more sources
Protease activity of plasma hemopexin [PDF]
Kidney International, 2005 Previous studies into the relevance of a putative circulating factor in the pathogenesis of minimal change nephrotic syndrome have opened the possibility that plasma hemopexin might be an important effector molecule in this disorder. Thus, intra renal infusion of isolated plasma hemopexin into rats induced minimal change like glomerular lesions and ...
Martin Harmsen +2 more
exaly +4 more sources
In Vivo Fate of Hemopexin and Heme-Hemopexin Complexes in the Rat
Archives of Biochemistry and Biophysics, 1993The disposition in the rat of the plasma heme-binding protein hemopexin (Hx), as the native apoprotein and as its heme complex (HHx), has been studied using the residualizing protein label dilactitol-125I-tyramine (*I-DLT). The aim of this work was to identify the tissue sites of Hx uptake and catabolism, independent of heme binding, and to evaluate ...
Potter, David W. +7 more
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International Journal of Immunopharmacology, 1984
Using a simple measurement system of hemopexin, single radial immunodiffusion-plate, the following results were obtained; firstly the normal level of hemopexin concentration in mouse was 0.55-1.25 mg ml-1. Secondly, antitumor agents were classified into two types on the basis of changes of hemopexin levels after administration of the agents. Finally, a
T, Ishiguro, K, Imanishi, I, Suzuki
openaire +2 more sources
Using a simple measurement system of hemopexin, single radial immunodiffusion-plate, the following results were obtained; firstly the normal level of hemopexin concentration in mouse was 0.55-1.25 mg ml-1. Secondly, antitumor agents were classified into two types on the basis of changes of hemopexin levels after administration of the agents. Finally, a
T, Ishiguro, K, Imanishi, I, Suzuki
openaire +2 more sources
Plasma Hemopexin Activity in Pregnancy and Preeclampsia
Hypertension in Pregnancy, 2007 Plasma hemopexin activity, associated with increased vascular permeability, was evaluated in healthy pregnant and non-pregnant women and in pre-eclamptic women.Hemopexin activity and the hemopexin inhibitor, extracellular ATP, were assayed in plasma from pregnant (n = 10), preeclamptic (n = 9), and non-pregnant women (n = 10) using standard methods ...
Jan G Aarnoudse +2 more
exaly +3 more sources