Results 51 to 60 of about 48,129 (210)

Hemophilia prevalence in Azerbaijan

, 2017
Aim. Assessment of hemophilia prevalence in Azerbaijan.Methods. Materials of the study were the data of the registry on hemophilia. Prevalence and its structure were calculated for the regions and towns of republican subordination: the number of ...
M M Kazimova, E A Kadimova
core   +1 more source

Adenovirus-based gene therapy approaches for hemophilia B [PDF]

, 2012
Gene therapy can be used to treat devastating inherited diseases, especially diseases and patients that are not suitable for a conventional cure. The blood clotting disorder hemophilia is one of the most extensively studied monogenetic diseases in gene ...
Zhang, Wenli
core   +1 more source

Guidelines for the management of hemophilia

, 2013
Hemophilia is a rare disorder that is complex to diagnose and to manage. These evidence-based guidelines offer practical recommendations on the diagnosis and general management of hemophilia, as well as the management of complications including ...
Mahlangu, J.N., Mulder, K., Poon, M. C., Mahlangu, J. N., Kitchen, S., Ludlam, C.A., Brewer, A. K., Mauser-Bunschoten, E.P., Srivastava, A., Brewer, A.K., Poon, M.C., Key, N. S., Ludlam, C. A., Street, A., Mauser?Bunschoten, E. P., Llinas, A., Key, N.S.   +16 more
core   +1 more source

Comparative Investigation of Thromboelastometry and Thrombin Generation for Patients Receiving Direct Oral Anticoagulants or Vitamin K Antagonists

Diagnostics
Background. Alterations induced by direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs) to thromboelastometry and thrombin generation are not well defined.
Armando Tripodi, Marco Capecchi, Erica Scalambrino, Marigrazia Clerici, Barbara Scimeca, Pasquale Agosti, Paolo Bucciarelli, Andrea Artoni, Flora Peyvandi   +8 more
doaj   +1 more source

Treatment adherence in hemophilia

, 2017
Courtney D Thornburg,1 Natalie A Duncan2 1Hemophilia and Thrombosis Treatment Center, Rady Children’s Hospital, San Diego, CA, 2Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, USA Abstract: Prophylactic clotting-factor regimens reduce
Thornburg CD, Duncan NA
core  

Gene therapy for hemophilia

, 2013
Hemophilia A and B are X-linked monogenic disorders resulting from deficiencies of factor VIII and FIX, respectively. Purified clotting factor concentrates are currently intravenously administered to treat hemophilia, but this treatment is non-curative ...
Chuah Lay Khim, Marinee, Evens, Hanneke, VandenDriessche, Thierry   +2 more
core   +1 more source

Hemophilia is associated with accelerated biological aging

Haematologica
Hemophilia is a rare X-linked bleeding disorder caused by mutations in the F8 or F9 gene (hemophilia A or B), leading to deficient factor VIII or IX proteins, respectively.
Marina Trappl, Rafaela Vostatek, Manuel Salzmann, Daniel Kraemmer, Johanna Gebhart, Philipp Hohensinner, Ingrid Pabinger, Cihan Ay   +7 more
doaj   +1 more source

The Health-Related Quality of Life scores and joint health in children and young adults with hemophilia

The Turkish Journal of Pediatrics
Background. Patients with hemophilia should be evaluated for joint health and overall health in their visits. The aims of this study were to evaluate joint health and health-related quality of life (HRQoL) in patients with mild, moderate, and severe ...
Buse Günyel, Mesut Bulakçı, Gamze Başkent, Ayşegül Ünüvar   +3 more
doaj   +1 more source

Gene Therapy in Hemophilia: Clinical Trials Update

, 2001
SummaryDisorders caused by inborn genetic errors have been a primary target for treatment by gene transfer. Hemophilia A and B have been considered especially important targets because the genes for factor VIII and IX are well characterized, levels of ...
Gilbert White
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Knowledge about hemophilia among teachers of patients with hemophilia in Indonesia

, 2020
Background: Hemophilia is a rare coagulation disorder of which not a lot of people are familiar with. Teachers of patient with hemophilia (PWH) have a substantial role in supporting school-aged PWH.
Silvia Wowiling, Stefanus Gunawan, Max Frans Jozef Mantik   +2 more
core   +1 more source