Results 61 to 70 of about 48,129 (210)
Identification of patients with congenital hemophilia in a large electronic health record database
Michael Wang,1 Anissa Cyhaniuk,2 David L Cooper,3 Neeraj N Iyer3 1Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, CO, 2AC Analytic Solutions, Barrington, IL, 3Clinical Development, Medical and Regulatory Affairs, Novo
Wang M, Iyer NN, Cyhaniuk A, Cooper DL
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Why is the uptake of gene therapy in hemophilia less than expected?
Gene therapy has held promise to cure hemophilia since factor (F)VIII and FIX were cloned more than 40 years ago. However, scientific understanding of the adeno-associated virus, the predominant vector used in gene therapy, has been insufficient to ...
Glenn F. Pierce +4 more
doaj +1 more source
Hussain I Saba, Duc Quang Tran, JrDepartment of Medicine, University of South Florida Medical Center, Tampa, FL, USAAbstract: In the past, patients with severe hemophilia have suffered a substantially reduced quality of life with frequent bleeding ...
Tran DQ Jr, Saba HI
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The management of hemophilia in elderly patients
Massimo Franchini1, Annarita Tagliaferri2, Pier Mannuccio Mannucci31Transfusion and Hemophilia Center, City Hospital of Verona, Italy; 2Regional Reference Center for Inherited Bleeding Disorders, University Hospital of Parma, Italy; 3Angelo Bianchi ...
M. Franchini +5 more
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Barriers and perceived limitations to early treatment of hemophilia
Kapil Saxena Boston Hemophilia Center, Boston Children’s Hospital, Boston, MA, USA Abstract: Early treatment of bleeds in hemophilia patients, both with and without inhibitors, has been shown to be of immense benefit in the overall clinical outcome.
Saxena K
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Discrepant ratios of arterial versus venous thrombosis in hemophilia A as compared with hemophilia B
The occurrence of thrombosis in patients with congenital bleeding disorders represents an exceptional event. Hemophilia A and hemophilia B patients have been showed to present both arterial and venous thrombosis (85 cases of arterial thrombosis and 34 ...
Irene Bertozzi +9 more
core +1 more source
Strategies to encourage physical activity in patients with hemophilia to improve quality of life
Miwa Goto,1 Hideyuki Takedani,2 Kazuhiko Yokota,1 Nobuhiko Haga3 1Rehabilitation Center, The University of Tokyo Hospital, 2Department of Joint Surgery, Research Hospital of the Institute of Medical Science, The University of Tokyo, 3Department of ...
Haga N, Yokota K, Goto M, Takedani H
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Bleeding matters:Perspectives on the clinical phenotype and management of hemophilia [PDF]
Hemophilia A and B are X-linked inherited coagulation disorders that are caused by a deficiency in coagulation factor VIII or IX, respectively. As a consequence, persons with hemophilia have an increased bleeding tendency.
Zwagemaker, A.-F.
core +1 more source
GlycoPEGylated recombinant factor IX for hemophilia B in context
Elena Santagostino, Maria Elisa Mancuso Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, IRCCS Ca’ Granda Foundation, Maggiore Hospital Policlinic, Milan, Italy Abstract: Decisions over hemophilia treatment selection and switching involve ...
Santagostino E, Mancuso ME
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Hemoaction game: an educational step to improve hemophilia children and nurses self-efficacy
As hemophilia is a chronic bleeding disease and can interfere with daily performance of children, these children require continuous training to prevent bleeding and take timely action (1).
NOOASHIN BEHESHTIPOOR +4 more
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