Results 71 to 80 of about 68,905 (210)
Hematology, 2006 Acquired hemophilia A is a rare but severe autoimmune bleeding disorder, resulting from the presence of autoantibodies directed against clotting factor VIII. The etiology of the disorder remains obscure, although approximately half of all cases are associated with other underlying conditions.
openaire +2 more sources
Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
, 2006 Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
core
Hemoaction game: an educational step to improve hemophilia children and nurses self-efficacy
Journal of Advances in Medical Education and Professionalism, 2016 As hemophilia is a chronic bleeding disease and can interfere with daily performance of children, these children require continuous training to prevent bleeding and take timely action (1).
NOOASHIN BEHESHTIPOOR +4 more
doaj
ORAL TREATMENT OF HEMOPHILIA [PDF]
, 2007 Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome.
Alpan, Oral +3 more
core +1 more source
Maximum Likelihood Estimation of the Multivariate Normal Mixture Model [PDF]
The Hessian of the multivariate normal mixture model is derived, and estimators of the information matrix are obtained, thus enabling consistent estimation of all parameters and their precisions.
Boldea, Otilia, Magnus, Jan R.
core +1 more source
Haemophilia B: an illustrative review of current challenges and opportunities
Research and Practice in Thrombosis and HaemostasisBackground: Hemophilia B is a genetic bleeding disorder caused by a deficiency of clotting factor IX, which presents unique challenges in clinical management.
Cedric Hermans +3 more
doaj +1 more source
Strengthening hemophilia registries globally: Strategies to improve patient outcomes
Iraqi Journal of HematologyHemophilia is a genetic bleeding disorder characterized by a deficiency of clotting factor VIII or IX. Hemophilia registries are structured databases that maintain longitudinal data on people diagnosed with hemophilia. Hemophilia registries maintained at
Saurabh RamBihariLal Shrivastava +3 more
doaj +1 more source
Patient and parent preferences for characteristics of prophylactic treatment in hemophilia
Patient Preference and Adherence, 2015 Roberto Furlan,1 Sangeeta Krishnan,2 Jeffrey Vietri3 1Advanced Methods, Kantar Health, Epsom, Surrey, UK; 2Global Health Economics and Outcomes Research, Biogen, MA, USA; 3Health Outcomes, Kantar Health, Milan, Italy Introduction: New longer-acting ...
Furlan R, Krishnan S, Vietri J
doaj
BMC Oral HealthBackground People with hemophilia commonly present with a range of bleeding symptoms, from minor oral cavity bleeds to life-threatening events such as intracranial hemorrhage.
Mathangi Kumar +3 more
doaj +1 more source
Bleeding, Thrombosis and Vascular BiologyBackground and Aims: Intracerebral hemorrhage (ICH) is a severe and life-threatening complication in patients with hemophilia, often resulting in high mortality and long-term neurological impairment.
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