Results 101 to 110 of about 78,600 (311)
ABSTRACT Introduction Despite factor (F)VIII prophylaxis, a perceived increased risk of bleeding for some people with severe haemophilia A (PwSHA) exists, limiting physical activity (PA) and restricting quality of life (QoL). Aim HemiNorth 2 (EudraCT# 2020‐003256‐32) is an interventional study evaluating the impact of switching from FVIII prophylaxis ...
Jan Astermark +9 more
wiley +1 more source
ABSTRACT Introduction Von Willebrand disease (VWD) is a bleeding disorder characterized by a deficiency or dysfunction of Von Willebrand factor (VWF) and/or Factor VIII (FVIII), critical coagulation proteins. Individuals with VWD often use combination oral contraceptives (COCs) to manage heavy menstrual bleeding.
Eve Justason +4 more
wiley +1 more source
Amy D Shapiro,1 Alejandro Fernandez,2 Jerome Teitel,3 Jaco Botha,2 Kate Khair4 1Indiana Hemophilia & Thrombosis Center, Indianapolis, IN, USA; 2Takeda Pharmaceutical International AG, Zürich, Switzerland; 3St.
Shapiro AD +4 more
doaj
Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A +4 more
core
ABSTRACT Introduction Heavy menstrual bleeding (HMB) is a common and burdensome symptom in women with von Willebrand disease (VWD). Although VWD and HMB have been studied, the prevalence and impact of HMB across different age groups remains underexplored. Aim To investigate the prevalence and impact of HMB in women with VWD across different age groups.
Anna Olsson +3 more
wiley +1 more source
Yanyu Wu,1 Shawn X Sun,1 Tao Fan2 1Global Evidence & Outcomes, Data Sciences Institute, Research and Development, Takeda Development Center Americas, Inc, Cambridge, MA, USA; 2US Health Economics and Outcomes Research, Takeda Pharmaceuticals USA, Inc ...
Wu Y, Sun SX, Fan T
doaj
ABSTRACT Introduction Although clinical experience of a triple‐secured, plasma‐derived, von Willebrand factor (pdVWF), almost devoid of Factor VIII (FVIII) in adults with von Willebrand disease (VWD), is widely reported, its use in children is less documented.
Jenny Goudemand +10 more
wiley +1 more source

