Results 101 to 110 of about 78,600 (311)

Health‐Related Quality of Life, Physical Activity and Joint Health in People With Severe Haemophilia A Receiving Emicizumab: Results From the Phase IV HemiNorth 2 Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Despite factor (F)VIII prophylaxis, a perceived increased risk of bleeding for some people with severe haemophilia A (PwSHA) exists, limiting physical activity (PA) and restricting quality of life (QoL). Aim HemiNorth 2 (EudraCT# 2020‐003256‐32) is an interventional study evaluating the impact of switching from FVIII prophylaxis ...
Jan Astermark   +9 more
wiley   +1 more source

Determining the Impact of Combination Oral Contraceptives on Von Willebrand Factor and Factor VIII in Healthy Patients and Patients With Von Willebrand Disease: A Scoping Review and Meta‐Analysis

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Von Willebrand disease (VWD) is a bleeding disorder characterized by a deficiency or dysfunction of Von Willebrand factor (VWF) and/or Factor VIII (FVIII), critical coagulation proteins. Individuals with VWD often use combination oral contraceptives (COCs) to manage heavy menstrual bleeding.
Eve Justason   +4 more
wiley   +1 more source

Final Results of the Prospective ADVATE® Immune Tolerance Induction Registry (PAIR) Study with Plasma- and Albumin-Free Recombinant Factor VIII

open access: yesJournal of Blood Medicine, 2021
Amy D Shapiro,1 Alejandro Fernandez,2 Jerome Teitel,3 Jaco Botha,2 Kate Khair4 1Indiana Hemophilia & Thrombosis Center, Indianapolis, IN, USA; 2Takeda Pharmaceutical International AG, Zürich, Switzerland; 3St.
Shapiro AD   +4 more
doaj  

Hemophilia. [PDF]

open access: green, 1899
A. J. Cook
openalex   +1 more source

Delivery of human apolipoprotein (apo) E to liver by an [E1(-), E3(-), polymerase(-), pTP(-)] adenovirus vector containing a liver-specific promoter inhibits atherogenesis in immunocompetent apoE-deficient mice [PDF]

open access: yes, 2006
Recombinant adenovirus (rAd)-mediated apoE gene transfer to the liver of apoE(-/-) mice is anti-atherogenic. However, first generation rAd vectors were associated with immune clearance of transduced hepatocytes, while an improved [E1(-), E3(-) polymerase(
Amalfitano, A   +4 more
core  

Prevalence and Impact of Heavy Menstrual Bleeding in Women With von Willebrand Disease Across Age Groups: A Retrospective Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Heavy menstrual bleeding (HMB) is a common and burdensome symptom in women with von Willebrand disease (VWD). Although VWD and HMB have been studied, the prevalence and impact of HMB across different age groups remains underexplored. Aim To investigate the prevalence and impact of HMB in women with VWD across different age groups.
Anna Olsson   +3 more
wiley   +1 more source

Comparison of Real-World Dose and Consumption for Two Extended Half-Life Recombinant Factor VIII Products for the Treatment of Hemophilia A in the United States

open access: yesJournal of Blood Medicine, 2022
Yanyu Wu,1 Shawn X Sun,1 Tao Fan2 1Global Evidence & Outcomes, Data Sciences Institute, Research and Development, Takeda Development Center Americas, Inc, Cambridge, MA, USA; 2US Health Economics and Outcomes Research, Takeda Pharmaceuticals USA, Inc ...
Wu Y, Sun SX, Fan T
doaj  

Strontium Lactate in Hemophilia [PDF]

open access: green, 1907
NULL AUTHOR_ID
openalex   +1 more source

Management of von Willebrand Disease With a Factor VIII‐Poor von Willebrand Factor Concentrate: Results From the Paediatric Cohort of a Prospective Observational Post‐Marketing Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Although clinical experience of a triple‐secured, plasma‐derived, von Willebrand factor (pdVWF), almost devoid of Factor VIII (FVIII) in adults with von Willebrand disease (VWD), is widely reported, its use in children is less documented.
Jenny Goudemand   +10 more
wiley   +1 more source

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