Results 131 to 140 of about 48,361 (234)

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan, Christiana‐Kondylo Sideri, Michael Henry, Selvaprakash Karuppuchamy, Esen Efeoglu, Paula Meleady   +5 more
wiley   +1 more source

Downstream Process Intensification for AAV Purification by Affinity Chromatography Using Single Pass Tangential Flow Filtration

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 174-185, January 2026.
ABSTRACT To enable adeno‐associated viral vectors (AAV) to achieve their maximum potential, next‐generation manufacturing processes must be developed to make gene therapies more affordable and accessible. This study focused on the design of two different intensified AAV downstream manufacturing processes at bench and pilot scale.
Akshay S. Chaubal, Ronny Horax, Christopher J. Yehl, S. Ranil Wickramasinghe, Xianghong Qian, Lu Wang, Andrew L. Zydney   +6 more
wiley   +1 more source

Nursing Care of a Patient Diagnosed with Hemophilia A Undergoing Coronary Artery Bypass Graft Surgery: A Case Report

, 2022
Tugba Albayram, Şükriye İlkay Güner
openalex   +1 more source

Antifibrinolytic therapy for preventing VWD-related postpartum hemorrhage: indications and limitations

Blood Advances, 2017
Peter A. Kouides
doaj   +1 more source

Evaluation of coagulation disorders and iron deficiency in women with heavy menstrual bleeding

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 250-254, January 2026.
Abstract Objective To explore the incidence of congenital bleeding disorders (CBD), which may result in anemia, in a large cohort of women referred for heavy menstrual bleeding (HMB) in a specialized gynecologic unit. Methods Between January 2022 and January 2024, all women referred for HMB were screened.
Lucia Rugeri, Yelena Fruchou, Caroline Brodbeck, Marianne Bastien, Amandine Lioux, Giulia Gouy, Marion Cortet, Gil Dubernard, Yesim Dargaud   +8 more
wiley   +1 more source

Health care resources and costs associated with delivering gene therapy for hemophilia in clinical practice. [PDF]

Res Pract Thromb Haemost
Prameyllawati DM, Mussert CMA, Oude Voshaar MAH, Lingsma HF, Cnossen MH, Coppens M, Meijer K, van der Valk PR, Leebeek FWG, Ten Ham RMT.   +9 more
europepmc   +1 more source

From Hip Effusion to Hemophilia: Unveiling the Cause of Pain in 6-Month-Old Infant. A Case Report. [PDF]

J Orthop Case Rep
Cadircibasi ER, Soylemez MS.
europepmc   +1 more source

Intra‐articular and intra‐osseous expanded adipose‐derived stromal cell injections for knee osteoarthritis‐related bone marrow lesions yield promising outcomes: Preliminary results in 16 athletes

Journal of Experimental Orthopaedics, Volume 13, Issue 1, January 2026.
Abstract Purpose To explore the results of a fluoroscopic‐guided intra‐osseous (IO) and intra‐articular (IA) injection of expanded adipose‐derived stromal cells (ASCs) in athletes with bone marrow lesions (BML) associated with knee osteoarthritis (OA).
Miguel A. Khoury, Emmanuel T. Papakostas, Theodorakys Marín Fermín, Montassar Tabben, Karim Chamari, Lorena Levi, Khaled Alkhelaifi, Pieter D'Hooghe   +7 more
wiley   +1 more source

Very low dislocation rate and good clinical outcome after Bereiter trochleoplasty and additional procedures following the Copenhagen patella–femoral instability algorithm: One‐ and two‐years outcomes from a consecutive cohort of 368 cases

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 1, Page 52-63, January 2026.
Abstract Purpose Patello–femoral instability (PFI) is often caused by predisposing factors, with trochlea dysplasia (TD) as the most prominent. Untreated patellar instability leads to impaired function and an increased risk of patellofemoral osteoarthritis.
Christian Dippmann, Volkert Siersma, Simone Rechter, Kristoffer W. Barfod, Peter Lavard   +4 more
wiley   +1 more source

Fitusiran (Qfitlia) as a first-in-class RNA interference therapeutic: targeting antithrombin for prophylactic hemostasis in hemophilia. [PDF]

Ann Med Surg (Lond)
Haider E, Preety F, Sheikh M, Akhtar R, Iloke CV, Oduoye MO.   +5 more
europepmc   +1 more source