Results 51 to 60 of about 22,597,991 (289)
The history and evolution of the clinical effectiveness of haemophilia type a treatment: a systematic review. [PDF]
, 2012 First evidence of cases of haemophilia dates from ancient Egypt, but it was when Queen Victoria from England in the 19th century transmitted this illness to her descendants, when it became known as the "royal disease".
A Aleem +48 more
core +2 more sources
Oman Journal of Ophthalmology, 2009 Hemophilic pseudotumor is an uncommon complication of factor VIII and IX deficiencies in the coagulation cascade and occurs in a wide spectrum of bones and soft tissues. We present a six-year-old boy with hemophilic pseudotumor localized in the right orbit.
Pooja Sethi +3 more
openaire +4 more sources
Journal of Orthopaedic Diseases and Traumatology, 2019 Background: Hemophilia A, an X-linked recessive disorder of coagulation, caused due to the deficiency of coagulation factor-VIII and hemophilia-B caused due to the deficiency of factor-IX cause spontaneous and traumatic bleeding episodes, leading to ...
Sujeet Mishra +3 more
doaj +1 more source
Bleeding Patterns among Severe Hemophilia A and B Patients in West Java
Althea Medical Journal, 2020 Background: The clinical manifestations of hemophilia A (HA) and hemophilia B (HB)are quite similar; however, the bleeding characteristics of these two hemophilia types have been reported to be different. This study aimed to explore the bleeding patterns
Muhammad Mufakkirul Islam +2 more
doaj +1 more source
Mortality in congenital hemophilia A – a systematic literature review
Journal of Thrombosis and Haemostasis, 2020 Against a background of a rapidly evolving treatment landscape, a contemporary, evidence‐based consolidated understanding of mortality in people with congenital hemophilia A (PwcHA) is lacking.
C. Hay, F. Nissen, S. Pipe
semanticscholar +1 more source
Endothelial cells derived from patients' induced pluripotent stem cells for sustained factor VIII delivery and the treatment of hemophilia A. [PDF]
, 2020 Hemophilia A (HA) is a bleeding disorder characterized by spontaneous and prolonged hemorrhage. The disease is caused by mutations in the coagulation factor 8 gene (F8) leading to factor VIII (FVIII) deficiency.
Agu, Emmanuel +9 more
core +1 more source
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. [PDF]
, 2001 Long-term expression of coagulation factor IX (FIX) has been observed in murine and canine models following administration of recombinant adeno-associated viral (rAAV) vectors into either the portal vein or muscle. These studies were designed to evaluate
Davidoff, A +5 more
core +1 more source
Utilization evaluation of factor concentration and frequencyof bleeds among patients with haemophilia "A" and haemophilia "B" in northwest Iran [PDF]
Journal of Analytical Research in Clinical Medicine, 2013 Background Haemophilia A and B are X-linked bleeding disorders which result in decreased blood levels of coagulants. According to some studies, Hemophilia Severity Score (HSS) is higher in severe Haemophilia A(HA) than in severe Haemophilia B(HB ...
Roya Dolatkhah +5 more
doaj +1 more source
Blood, 2019 Emicizumab, a bispecific humanized monoclonal antibody, bridges activated factor (F) IX and FX to restore the function of missing activated FVIII in hemophilia A.
G. Young +15 more
semanticscholar +1 more source