Results 101 to 110 of about 13,000,271 (286)

Hemophilia B: molecular pathogenesis and mutation analysis

Journal of Thrombosis and Haemostasis, 2015
Hemophilia B is an X‐chromosome‐linked inherited bleeding disorder primarily affecting males, but those carrier females with reduced factor IX activity (FIX:C) levels may also experience some bleeding.
A. Goodeve
semanticscholar   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Emergencies in Hemophiliacs

Journal of Education and Teaching in Emergency Medicine, 2016
Audience: This modified team-based learning (mTBL) session is appropriate for medical students or emergency medicine residents. Introduction: Hemophilia is an x-linked recessive disorder leading to a decrease in functional clotting factors; there ...
Alisa Wray
doaj   +1 more source

Hemophilia B in a Pair of Monozygotic Negro Twins [PDF]

, 1964
Israel Roisenberg
openalex   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Evaluation of the Clinical Status of Patients with Inherited Bleeding Disorders in Diyala-Iraq

Diyala Journal of Medicine, 2019
Background: Inherited bleeding disorders are rare diseases that are both complicated and expensive to manage, they are classified into: coagulation factor disorders, vessel wall defect and platelet disorders.
Imad Ahmed Lateef
doaj   +2 more sources

Defibrination Syndrome Developed after Replacement Therapy with PPSB in a Case of Hemophilia B. [PDF]

, 1977
Mutsuyoshi Kazama, H Iwakura, Masaru Nakajima, M. Abe, Tetsuya Abe   +4 more
openalex   +1 more source

Expression and Linkage of Genes for X-linked Hemophilias A and B in the Dog [PDF]

, 1973
K. M. Brinkhous, Peter D. Davis, John B. Graham, W. Jean Dodds   +3 more
openalex   +1 more source

Prophylactic efficacy of BeneFIX vs Alprolix in hemophilia B mice.

Blood, 2016
FIX binds tightly to collagen IV. Furthermore, a FIX mutant, FIXK5R, which binds better than wild-type FIX to collagen IV, provides better hemostasis than wild-type FIX, long after both are undetectable in the plasma.
B. Cooley, W. Funkhouser, D. Monroe, Ashley Ezzell, D. Mann, F. Lin, P. Monahan, D. Stafford   +7 more
semanticscholar   +1 more source

Physical Activity Awareness and Understanding of Treatment Protection Among People With Haemophilia and Their Caregivers in Central Europe

Haemophilia, EarlyView.
ABSTRACT Background Physical activity is now considered generally beneficial for persons with haemophilia (PWH). However, the specific type and extent of activity and its impact on quality of life (QoL) and bleed protection during exercise is under‐researched.
Angelika Batorova, Atanas Banchev, Ana Boban, Brigitte Brand, Melen Brinza, Barbara Faganel Kotnik, Csongor Kiss, Gediminas Puras, Jan Rajnoch, Ester Zapotocka   +9 more
wiley   +1 more source