Results 131 to 140 of about 13,000,271 (286)

Alternative Immunosuppression in Acquired Haemophilia A

Haemophilia, EarlyView.
Jayna Mistry, Gillian Lowe, Will Lester, Charles Percy   +3 more
wiley   +1 more source

Estimating the Factor VIII‐Equivalent Activity of Emicizumab Using Global Assays of Haemostasis

Haemophilia, EarlyView.
ABSTRACT Background Emicizumab is a bispecific monoclonal antibody mimicking factor (F) VIII activity and an effective therapy for prophylaxis in people with haemophilia A (PWHA). The FVIII‐equivalent activity (FVIIIeq) of emicizumab remains unknown. Objectives To estimate FVIIIeq of emicizumab using global assays of haemostasis.
Daniel Kraemmer, Cihan Ay, Judit Rejtő, Georg Heinze, Peter Quehenberger, Ingrid Pabinger, Oliver Königsbrügge   +6 more
wiley   +1 more source

Splice junction mutations in factor IX gene resulting in severe hemophilia B [PDF]

, 1991
S.H. Chen, Miqin Zhang, Arthur R. Thompson, Gordon L. Bray, C. Ronald Scott   +4 more
openalex   +1 more source

Radiological Stage of Hemophilic Arthropathy of Knee Does Not Correlate With Clinical Variables

Haemophilia, EarlyView.
ABSTRACT Background Various functional and radiological systems have been developed to evaluate joint health and the severity of arthropathy in hemophilic patients. Clinical relevance of these radiological systems has received minimal attention. Methods Through a retrospective chart review, 84 patients with end‐stage hemophilic arthropathy of the knee ...
Arman Vahabi, Erdem Er, Abdussamet Kuyucu, Elcil Kaya Biçer, Semih Aydoğdu   +4 more
wiley   +1 more source

Clinical audit of inherited bleeding disorders in a developing country

Indian Journal of Pathology and Microbiology, 2010
Objective: We did a clinical audit to determine the status of coagulation disorders in a hemophilia care center in Pakistan. Setting: Fatimid foundation blood bank and hematological diseases center, Lahore.
Sajid Raihan, Khalid Safoorah, Mazari Nazish, Azhar Waleed, Khurshid Mohammad   +4 more
doaj  

Spinal Stenosis: An Emerging Complication of Ageing in People With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Advances in haemophilia care have brought the challenges of ageing for people with haemophilia (PWH) to the forefront. Age‐related spinal degeneration may result in spinal stenosis; however, the rates in PWH are unknown. We sought to systematically review Irish PWH to address this gap in the current literature.
Claire Kelly, Mark McGowan, Niamh Larkin, Jake M. Mc Donnell, Anne‐Marije Hilshof, Mary Byrne, Catherine Bergin, Aine O'Gara, Kevin Ryan, Mairead O'Donovan, Niamh O'Connell, Keith Synnott, Joseph S. Butler, Stacey Darwish, Brian O'Mahony, Megan Kennedy, Peter L. Turecek, James S. O'Donnell, John Gormley, Michelle Lavin   +19 more
wiley   +1 more source

Qualification Criteria of Gene Therapy for Haemophilia—Opinion of the EAHAD Gene Therapy Working Group

Haemophilia, EarlyView.
Abstract Background Following the approval of the first gene therapies for haemophilia, it is essential to develop an optimal infrastructure for the administration of gene therapy. This can be ensured by identifying the criteria for the definition of treatment centres (hub centres) and follow‐up centres (spoke centres), as well as establishing ...
Wolfgang Miesbach, Ana Boban, Pratima Chowdary, Michiel Coppens, Victor Jimenez‐Yuste, Robert Klamroth, Greta Mulders, Miguel Crato, Flora Peyvandi   +8 more
wiley   +1 more source

Nephrotic Syndrome as a Complication of Immune Tolerance in Hemophilia B [PDF]

, 1997
Bruce M. Ewenstein, C. Takemoto, Indira Warrier, Jeanne M. Lusher, P. Saidi, Joan Eisele, Lawrence J. Ettinger, Donna DiMichele   +7 more
openalex   +1 more source

The Roles and Clinical Significance of Major Hepatic‐Derived Metabolites in Hepatocellular Carcinoma

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) is increasingly recognized as a metabolically orchestrated malignancy, in which hepatic‐derived metabolites function not only as byproducts of liver physiology but also as active modulators of tumor biology.
Rui Sun, Xiaoru Wang, Jiayi Ma, Yuying Cai, Lei Li, Shanshan Wang   +5 more
wiley   +1 more source

Hemophilia B Gene Therapy with a High‐Specific‐Activity Factor IX Variant

New England Journal of Medicine, 2017
Lindsey A. George, S. Sullivan, A. Giermasz, J. Rasko, B. Samelson-Jones, J. Ducore, A. Cuker, L. Sullivan, S. Majumdar, J. Teitel, C. McGuinn, M. Ragni, A. Luk, Daniel J. Hui, Fraser Wright, Yifeng Chen, Yun Liu, Katie Wachtel, Angela Winters, S. Tiefenbacher, V. Arruda, J. C. M. van der Loo, O. Zelenaia, D. Takefman, M. Carr, L. Couto, X. Anguela, K. High   +27 more
semanticscholar   +1 more source