Factor VIII Antibodies Demonstrate Type I or Type II Kinetics in Acquired Haemophilia A
ABSTRACT Background Acquired haemophilia A (AHA) is an acquired bleeding disorder resulting from autoantibodies against Factor VIII (FVIII). Previous studies have reported differences in FVIII inhibitor kinetics (type I or type II) in AHA compared to severe haemophilia A.
Kirollos Kamel+4 more
wiley +1 more source
Sharp Inequalities between Harmonic, Seiffert, Quadratic and Contraharmonic Means [PDF]
In this paper, we present the greatest values $\alpha$, $\lambda$ and $p$, and the least values $\beta$, $\mu$ and $q$ such that the double inequalities $\alpha D(a,b)+(1-\alpha)H(a,b)
arxiv
Hemophilia B: molecular pathogenesis and mutation analysis
Hemophilia B is an X‐chromosome‐linked inherited bleeding disorder primarily affecting males, but those carrier females with reduced factor IX activity (FIX:C) levels may also experience some bleeding.
A. Goodeve
semanticscholar +1 more source
TREATMENT OF HEMOPHILIA WITH HUMAN FACTORIX PRODUCED IN MAMIMARY TISSUE OF TRANSGENIC MAMMALS [PDF]
Recombinant Factor IX characterized by a high percentage of active protein can be obtained in the milk of transgenic animals that incorporate chimeric DNA molecules according to the present invention.
Drohan, William N.+4 more
core +1 more source
A Girl with Hemorrhagic Diathesis in a Family of Mild Hemophilia B (Female Hemophilia B?)
Female carriers of hemophilia are usually asymptomatic. Female hemophilia B or symptomatic carriers of hemophilia B are extremely rare and so far only 16 cases have been reported.We report a girl with hemorrhagic diathesis in a family of mild hemophilia B, who was suspected female hemophilia B.
Takeshi Nagao, Atsuo Iizuka
openaire +3 more sources
ABSTRACT Introduction Clinical trials and real‐world evidence have demonstrated the efficacy and safety of rVIII‐SingleChain in previously treated patients with haemophilia A. Aim To investigate the safety and efficacy of rVIII‐SingleChain in previously untreated patients (PUPs).
Johnny Mahlangu+13 more
wiley +1 more source
On Group bijections $φ$ with $φ(B)=A$ and $\forall a\in B, aφ(a) \notin A$ [PDF]
A {\em Wakeford pairing} from $S$ onto $T$ is a bijection $\phi : S \to T$ such that $x\phi(x)\notin T,$ for every $x\in S.$ The number of such pairings will be denoted by $\mu(S,T)$. Let $A$ and $ B$ be finite subsets of a group $G$ with $1\notin B$ and $|A|=|B|.$ Also assume that the order of every element of $B$ is $\ge |B|$. Extending results due
arxiv
Systematic Literature Review of Outcomes Associated With Adherence to Haemophilia Drug Therapy
ABSTRACT Introduction Prophylactic therapy improves clinical and quality of life (QoL) outcomes in patients with haemophilia; however, this effect could be influenced by the degree of treatment adherence. Adherence to therapy may be difficult due to the administration mode and the frequency of self‐infusions.
Cynthia Khanji+6 more
wiley +1 more source
Some examples of two-dimensional regular rings [PDF]
Let B be a ring and $A=B[X,Y]/(aX^2+bXY+cY^2-1)$ where $a,b,c\in B$. We study the smoothness of A over B, and the regularity of B when B is a ring of algebraic integers.
arxiv
"Diagnosis of Hemophilia B Carriers, Using Taq I and Xmn I Polymorphisms of the FactorIX Gene in Iranian Individuals" [PDF]
Hemophilia B is factor IX deficiency and is inherited as X-linked recessive disorder. The subject of carrier detection in hemophilias has received new impetus in the last several years.
P Ghandil+3 more
doaj +2 more sources