Shared Human/Rabbit Ligands for Rabbit Hemorrhagic Disease Virus
To the Editor: Rabbit hemorrhagic disease virus (RHDV) is a calicivirus of the genus Lagovirus that causes epidemics of an acute disease and mortality rates of 50%–90% among rabbits. The disease, which was first described in 1984, is characterized by hemorrhagic lesions, mainly affecting the liver and lungs 24–72 h after infection (1).
Béatrice Le Moullac-Vaidye+3 more
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Changes in MicroRNA Expression during Rabbit Hemorrhagic Disease Virus (RHDV) Infection [PDF]
Current knowledge on the role of microRNAs (miRNAs) in rabbit hemorrhagic disease virus (RHDV) infection and the pathogenesis of rabbit hemorrhagic disease (RHD) is still limited. RHDV replicates in the liver, causing hepatic necrosis and liver failure.
Beata Hukowska-Szematowicz+6 more
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Capsid gene divergence in rabbit hemorrhagic disease virus
The emergence and rapid global spread of rabbit hemorrhagic disease virus (RHDV) remains enigmatic despite two decades of study, largely due to the difficulties associated with modelling substitution processes of the RNA genome for phylogenetic inference. We used maximum-likelihood and Bayesian methods to investigate rates of molecular evolution in the
Kinnear, Mark, Linde, Celeste
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Comparative Phylodynamics of Rabbit Hemorrhagic Disease Virus in Australia and New Zealand [PDF]
ABSTRACTThe introduction of rabbit hemorrhagic disease virus (RHDV) into Australia and New Zealand during the 1990s as a means of controlling feral rabbits is an important case study in viral emergence. Both epidemics are exceptional in that the founder viruses share an origin and the timing of their release is known, providing a unique opportunity to ...
Janine A. Duckworth+10 more
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Outbreak of Rabbit Hemorrhagic Disease Virus 2 Infections, Ghana [PDF]
Abstract In September 2019, high mortality in commercial rabbits was reported in the Greater Accra Region of Ghana. Rabbit hemorrhagic disease virus 2 phylogenetically related to isolates from 2015–2017 outbreaks in the Netherlands was confirmed as the causative agent. The virus has not yet been detected in native rabbits in Ghana.
Aruna Ambagala+6 more
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Hemagglutination and Antigenic Comparison of Rabbit Hemorrhagic Disease Virus.
The hemagglutinating activity and serological properties of three strains of rabbit hemorrhagic disease virus, Chinese, Korean and Shizuoka, which was first isolated in Japan, were examined by hemagglutination (HA) and cross hemagglutination inhibition (HI) test with human erythrocytes.
Ken-ichi Itou+2 more
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Emerging Rabbit Hemorrhagic Disease Virus 2 (RHDVb), Australia
To the Editor: In May 2015 an isolate of the recently emerged variant of rabbit hemorrhagic disease virus (RHDV), RHDV2, was identified in an Australian wild rabbit (Oryctolagus cuniculus). RHDV2 (also called RHDVb) was first described in outbreaks in France in 2010 (1), then Italy and Spain in 2011 (2,3) and in Portugal from 2012 onwards (4).
Tanja Strive+5 more
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EFFICACY OF A NEW ISOLATE RABBIT HEMORRHAGIC DISEASE VIRUS VACCINE [PDF]
The present study was carried out to prepare and evaluate an inactivated vaccine from new isolate rabbit hemorrhagic disease (RHD) virus that causes outbreaks in rabbit flocks vaccinated with commercially available vaccines. Sixty, 3 months old New Zealand rabbits were allotted into four groups (A, B, C, D).
M. M . Ismail+3 more
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Protection against myxomatosis and rabbit viral hemorrhagic disease with recombinant myxoma viruses expressing rabbit hemorrhagic disease virus capsid protein [PDF]
Two myxoma virus-rabbit hemorrhagic disease virus (RHDV) recombinant viruses were constructed with the SG33 strain of myxoma virus to protect rabbits against myxomatosis and rabbit viral hemorrhagic disease. These recombinant viruses expressed the RHDV capsid protein (VP60).
Bertagnoli, Stéphane+9 more
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Case series: Four fatal rabbit hemorrhagic disease virus infections in urban pet rabbits
Four pet rabbits (Oryctolagus cuniculus cuniculus) diagnosed with a fatal infection by rabbit hemorrhagic disease virus (RHDV GI.2) were identified in the same week and further investigated. All animals lived in an urban environment (Lisbon, Portugal), were between 8 months and 2 years old and none had been vaccinated against RHDV2 (GI.2).
Filipe Fontes Pinto+11 more
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