Results 91 to 100 of about 17,340 (217)

Persistence and Organ Tropism of Filoviruses in Farmed European Perch (Perca fluviatilis)

Journal of Fish Diseases, Volume 49, Issue 5, May 2026.
Johanna Perschthaler, Nicole Wildi, Lena K. Matthiss, Torsten Seuberlich, Heike Schmidt‐Posthaus   +4 more
wiley   +1 more source

Ebola Virus Disease Preparedness in Subnational Health Systems: A Readiness Assessment of Jinja District, Uganda

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Ebola virus disease (EVD) remains a significant public health threat in sub‐Saharan Africa. Jinja District in Uganda has experienced two EVD outbreaks in the recent past, first in November 2022 and again in February 2025, positioning it among the country’s EVD hotspots during Uganda’s eight recorded outbreaks.
Joseph Oposhia, Joseph M. Kungu, Peter Dyogo Nantamu, Josephine Namayanja, Charles A. B. Okuyo, Michael Mulowoza, Kenneth Kabali, Katushabe Edson, Peter Olupot-Olupot, Rajib Chowdhury   +9 more
wiley   +1 more source

Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective

Frontiers in Immunology
Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health ...
Duane C. Harris, Apoorv Shanker, Makaela M. Montoya, Trent R. Llewellyn, Anna R. Matuszak, Aditi Lohar, Jessica Z. Kubicek-Sutherland, Ying Wai Li, Kristen Wilding, Ben Mcmahon, Sandrasegaram Gnanakaran, Ruy M. Ribeiro, Alan S. Perelson, Carmen Molina-París   +13 more
doaj   +1 more source

Transboundary Animal Diseases Associated With Cross‐Border Camel Movement. A Systematic Review and Meta‐Analysis

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Transboundary animal diseases (TADs) are contagious diseases that significantly impact livestock health, public health and economic stability. In regions with frequent cross‐border trade and transhumance involving camels, particularly the Middle East and Africa, TADs pose a heightened One Health risk due to their zoonotic potential and capacity to ...
Alex A. Adikwu, Theophilus I. Emeto, Paul F. Horwood, Olajide A. Owolodun, Andrew M. Adamu, Oyelola A. Adegboye, Abdelfattah Selim   +6 more
wiley   +1 more source

Ecologic and Geographic Distribution of Filovirus Disease

Emerging Infectious Diseases, 2004
We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses.
A. Townsend Peterson, John T. Bauer, James N. Mills   +2 more
doaj   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Discovery and Description of Ebola Zaire Virus in 1976 and Relevance to the West African Epidemic During 2013-2016. [PDF]

, 2016
BACKGROUND: In 1976, the first cases of Ebola virus disease in northern Democratic Republic of the Congo (then referred to as Zaire) were reported. This article addresses who was responsible for recognizing the disease; recovering, identifying, and ...
Breman, Joel G, Heymann, David L, Johnson, Karl M, Lloyd, Graham, McCormick, Joseph B, Miatudila, Malonga, Murphy, Frederick A, Muyembé-Tamfun, Jean-Jacques, Piot, Peter, Ruppol, Jean-François, Sureau, Pierre, van der Groen, Guido   +11 more
core   +1 more source

Identification of TPRA1 as a Novel Receptor and Predictive Biomarker for Oncolytic Virus M1

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies transmembrane protein adipocyte‐associated 1 (TPRA1) as a novel receptor for oncolytic virus M1 (OVM). TPRA1's ectodomain binds OVM particles, while its intracellular domain facilitates virus internalization, promoting efficient viral entry.
Linyi Hu, Guigen Zhang, Yuan Lin, Shiming Yi, Jingyu Yang, Xueying Lin, Deli Song, Zhiheng Liu, Jiayu Zhang, Ying Zeng, Shanyu Huang, Zhen Fan, Jifu Zhang, Ying Liu, Cheng Hu, Wenbo Zhu, Wei Yin, Jun Hu, Guangmei Yan, Jing Cai, Jiankai Liang   +20 more
wiley   +1 more source

Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study

ChemistryOpen, Volume 14, Issue 12, December 2025.
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman, Gamal A. H. Mekhemer, Peter A. Sidhom, Mohamed A. El‐Tayeb, Shahzeb Khan, Mahmoud A. A. Ibrahim   +5 more
wiley   +1 more source

Convalescent plasma. New evidence for an old therapeutic tool? [PDF]

, 2016
Passive immunisation for the prevention and treatment of human infectious diseases can be traced back to the 20th century. The recent Ebola virus outbreak in West Africa has turned the spotlight onto the possible use of convalescent whole blood and ...
Catalano, Liviana, Facco, Giuseppina, Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +6 more
core   +1 more source