A Mouse Model for Evaluation of Prophylaxis and Therapy of Ebola Hemorrhagic Fever [PDF]
The Zaire subtype of Ebola virus (EBO-Z) is lethal for newborn mice, but adult mice are resistant to the virus, which prevents their use as an animal model of lethal Ebola infection. We serially passed EBO-Z virus in progressively older suckling mice, eventually obtaining a plaque-purified virus that was lethal for mature, immunocompetent BALB/c and ...
Bray, Mike+4 more
openaire +5 more sources
Forensic Epidemiology: Bridging Public Health and Legal Investigations to Address Modern Challenges
Image generated using Canva's Text‐to‐Image feature, www.canva.com/ai‐image‐generator [4 February 2025]. ABSTRACT Forensic epidemiology (FE) is a multi‐disciplinary field that applies epidemiologic principles and methods to collate and analyze trends and associations among medical and scientific examinations of adverse health outcomes with criminal or ...
J. L. Schumann+3 more
wiley +1 more source
Ebola Hemorrhagic Fever as a Public Health Emergency of International Concern; a Review Article
Ebola hemorrhagic fever (EHF) was first reported in 1976 with two concurrent outbreaks of acute viral hemorrhagic fever centered in Yambuku (near the Ebola River), Democratic Republic of Congo, and also in Nzara, Sudan.
Saeed Safari+4 more
doaj
Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health ...
Duane C. Harris+13 more
doaj +1 more source
Ecologic and Geographic Distribution of Filovirus Disease
We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses.
A. Townsend Peterson+2 more
doaj +1 more source
Infrastructure and methods for real-time predictions of the 2014 dengue fever season in Thailand [PDF]
Epidemics of communicable diseases place a huge burden on public health infrastructures across the world. Producing accurate and actionable forecasts of infectious disease incidence at short and long time scales will improve public health response to outbreaks.
arxiv
Point-of-Care Ultrasound Assessment of Tropical Infectious Diseases—A Review of Applications and Perspectives [PDF]
The development of good quality and affordable ultrasound machines has led to the establishment and implementation of numerous point-of-care ultrasound (POCUS) protocols in various medical disciplines.
Abdalla+111 more
core +5 more sources
Ebola Hemorrhagic Fever(EHF): Mechanism of Transmission and Pathogenicity.
Hemorrhagic fevers represent a wide spectrum of viral infectious diseases, out-breaking mostly as epidemics, some of them being highly lethal. They range from those caused by bunyaviridae, associated with renal or pulmonary syndromes and those recently emerging and caused by the filoviridae family of thread-like viruses.
Masumi Shimizu+5 more
openaire +4 more sources
Ebola hemorrhagic fever: current outbreak and progress in finding a cure [PDF]
As reported: “A health care worker at Texas Health Presbyterian Hospital, who cared for dying Ebola patient has been tested positive for the virus after a preliminary test, officials said early Sunday. If confirmed, it would be the first known person-to-person transmission of the disease in the United States” [1].
Soodabeh Saeidnia, Mohammad Abdollahi
openaire +3 more sources
Ebolavirus evolution and emergence are associated with land use change
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange+8 more
wiley +1 more source