Results 81 to 90 of about 17,390 (200)

Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health

Microbial Biotechnology, Volume 18, Issue 9, September 2025.
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley   +1 more source

Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective

Frontiers in Immunology
Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health ...
Duane C. Harris, Apoorv Shanker, Makaela M. Montoya, Trent R. Llewellyn, Anna R. Matuszak, Aditi Lohar, Jessica Z. Kubicek-Sutherland, Ying Wai Li, Kristen Wilding, Ben Mcmahon, Sandrasegaram Gnanakaran, Ruy M. Ribeiro, Alan S. Perelson, Carmen Molina-París   +13 more
doaj   +1 more source

Ecologic and Geographic Distribution of Filovirus Disease

Emerging Infectious Diseases, 2004
We used ecologic niche modeling of outbreaks and sporadic cases of filovirus-associated hemorrhagic fever (HF) to provide a large-scale perspective on the geographic and ecologic distributions of Ebola and Marburg viruses.
A. Townsend Peterson, John T. Bauer, James N. Mills   +2 more
doaj   +1 more source

Inhibition of the Clathrin Terminal Domain—Amphiphysin Protein–Protein Interaction. Probing the Pitstop 2 Aromatic Moiety

ChemMedChem, Volume 20, Issue 16, August 16, 2025.
Pitstop 2 binds to the clathrin terminal domain. This work explores the nature of the benzylidene moiety, R. The synthesis of 56 novel analogues reveals enhanced potency of a multiple analogues, with catechol‐free 2,3‐dihydroxybenzo[b][1,4]dioxone (54) returning a 1.2 μm IC50, ca 10‐fold more active than Pitstop 2. Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)
Kate Prichard, Mark J. Robertson, Ngoc Chau, Jing Xue, Martin Neuenschwander, Uwe Fink, Andre Horatscheck, Marc Nazare, Phillip J. Robinson, Volker Haucke, Adam McCluskey   +10 more
wiley   +1 more source

Automatic Classification of the Movements of Directed and Undirected Subviral Particles

Current Directions in Biomedical Engineering, 2020
The development of drugs against pathogens that cause hemorrhagic fever, such as Marburg and Ebola virus, requires researchers to gather much information about the virus.
Kaak Michelle, Rausch Andreas, Schanze Thomas   +2 more
doaj   +1 more source

The Ebola virus disease outbreak in Tonkolili district, Sierra Leone: a retrospective analysis of the Viral Haemorrhagic Fever surveillance system, July 2014–June 2015 [PDF]

, 2019
In Sierra Leone, the Ebola virus disease (EVD) outbreak occurred with substantial differences between districts with someone even not affected. To monitor the epidemic, a community event-based surveillance system was set up, collecting data into the ...
Colizzi, Vittorio, DJEUNANG DONGHO, GHYSLAINE BRUNA, Miglietta, Alessandro, Montesano, Carla, Rezza, Giovanni, Russo, Gianluca, Solimini, ANGELO GIUSEPPE, Vullo, Vincenzo   +7 more
core   +1 more source

Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease

Emerging Infectious Diseases, 2016
We report a case of probable Zaire Ebola virus–related ophthalmologic complications in a physician from the United States who contracted Ebola virus disease in Liberia.
John R. Chancellor, Sriranjani P. Padmanabhan, Thomas C. Greenough, Richard Sacra, Richard T. Ellison, Lawrence C. Madoff, Rebecca J. Droms, David M. Hinkle, George K. Asdourian, Robert W. Finberg, Ute Stroher, Timothy M. Uyeki, Olga M. Cerón   +12 more
doaj   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Analysis of the Impact Consequent to the Emergence of Imported Ebola Virus Disease Cases in the Russian Federation

Проблемы особо опасных инфекций, 2015
Objective of the study was to forecast the scale of the outbreak that would emerge after arrival of persons infected with Ebola virus into the Russian Federation.
V. B. Kirillov, S. L. Kirillova, S. V. Borisevich   +2 more
doaj   +1 more source

Research progress Ebola Hemorrhagic Fever vaccine

Journal of Applied Virology, 2015
<p>Ebola hemorrhagic fever is a potent infectious disease by Ebola virus caused 90% mortality rate. Ebola virus was first isolated in 1976 by, for single-stranded negative segment, non-segmented, enveloped RNA viruses belonging to filamentous virus family. Ebola virus can be divided into five different subtypes.
Yunpeng Wang, Yuchen Zhang
openaire   +1 more source