Results 101 to 110 of about 119,290 (297)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li   +3 more
wiley   +1 more source

Complement in Human Serum Suppresses Antibody- Dependent Enhancement and Potentiates Neutralization of Dengue Virus

open access: yesSiriraj Medical Journal
Objective: Antibody-dependent enhancement (ADE), in which pre-existing antibodies increase viral infection, is a major concern in dengue virus (DENV) pathogenesis and vaccine development.
Hansa Praneechit   +3 more
doaj   +1 more source

A fatal yellow fever virus infection in China: description and lessons

open access: yesEmerging Microbes and Infections, 2016
Yellow fever (YF) is a viral disease endemic to the tropical regions of Africa and South America. An outbreak of YF has been occurring in Angola, since the beginning of 2016.
Zhihai Chen   +26 more
doaj   +1 more source

Phenotypic and Molecular Characterization of Naganishia uzbekistanensis: Diagnostic Challenges and Antifungal Resistance Profile

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
The graphical abstract summarizes the laboratory characterization of Naganishia uzbekistanensis strain CY11558. The isolate shows distinct colony morphology, globular yeast cells with a fibrillar surface network under scanning electron microscopy, and a weakly positive cryptococcal antigen reaction.
Xin Fan   +7 more
wiley   +1 more source

Epidemiological and virological differences in human clustered and sporadic infections with avian influenza A H7N9

open access: yesInternational Journal of Infectious Diseases, 2016
Background: Previous research has suggested that avian influenza A H7N9 has a greater potential pandemic risk than influenza A H5N1. This research investigated the difference in human clustered and sporadic cases of H7N9 virus and estimated the relative ...
Zuqun Wu   +8 more
doaj   +1 more source

Incidence, contributing factors, and predictors of diagnostic errors in medical inpatients: A retrospective cohort study

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Diagnostic error is a major patient safety concern in hospitals, yet most studies have focused on selected high‐risk subgroups, leaving the broader general internal medicine inpatient population understudied. Objectives To determine the incidence, contributing factors, resulting harm, and predictors of diagnostic error in medical ...
Caterina E. Marx   +9 more
wiley   +1 more source

Aplikasi Sistem Informasi Geografis Penyebaran Penyakit Demam Berdarah Dengue Berbasis Web (Studi Kasus : Kabupaten Kudus) [PDF]

open access: yes, 2014
One of the common diseases which often occur in the region in Indonesia is Dengue Hemorrhagic Fever. Geographic information system (GIS) is one of the tools which can be used to deliver information of disease distribution and to help analyze the area ...
Sudarsono, B. (Bambang)   +2 more
core  

The “5L” framework of diagnostic reasoning: A stepwise scaffold to support clinician educators

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Diagnostic reasoning (DR) is a core clinical skill, yet its teaching remains variable. We introduce the “5L” framework as a bedside teaching scaffold that gives educators and learners a shared, stepwise set of prompts for DR during individual encounters. By asking, “What's Lethal? What's Likely? What's Logical? What's Lurking?
Olivia Brumfield   +3 more
wiley   +1 more source

Diagnostic Performance of Ultrasound in Adult Appendicitis. A Retrospective Review of 331 Cases

open access: yesJournal of Medical Radiation Sciences, EarlyView.
The sensitivity of ultrasound in the detection of appendicitis had a prevalence of 16% in our predominantly young female cohort, with alternative gynaecological and abdominal diagnoses identified approximately 2:1. The sensitivity for ultrasound to detect appendicitis was 60%, with specificity of 98% and negative predictive value (NPV) of 93%.
Alistair Lock, Martin Necas
wiley   +1 more source

Myeloid sarcoma presenting as an isolated pancreatic mass in a 3‐year‐old child

open access: yesJPGN Reports, EarlyView.
Abstract Myeloid sarcoma (MS) is an extramedullary tumor of myeloid precursor cells, frequently associated with acute myeloid leukemia (AML), and rarely occurring in isolation. We present a child with obstructive jaundice secondary to a pancreatic head mass.
Jappmann Kaur Monga   +7 more
wiley   +1 more source

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