Results 61 to 70 of about 952,590 (241)

Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis

mBio
Dengue virus (DENV) infection poses a significant global health threat, yet our understanding of its immunopathogenesis remains incomplete due to limitations of existing models.
Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa, Yupin Suputtamongkol, Wannee Limpitikul, John P. Atkinson, Panisadee Avirutnan   +13 more
doaj   +1 more source

Evaluation of antigen and antibody assays for surveillance of Lassa virus in peri-domestic rodents in southeastern Sierra Leone: a cross-sectional study

The Lancet Microbe
Summary: Background: Lassa fever, caused by Lassa mammarenavirus (LASV), is a rodent-borne disease endemic to west Africa. Zoonotic surveillance of LASV provides epidemiological insights into its potential presence.
Allison R Smither, PhD, James Koninga, Franklyn B Kanneh, MS, Momoh Foday, Matthew L Boisen, PhD, Nell G Bond, PhD, Mambu Momoh, MS, John D Sandi, PhD, Lansana Kanneh, HD, Foday Alhasan, BS, Ibrahim M Kanneh, HD, Mohamed S Yillah, Donald S Grant, MBChB, Duane J Bush, MS, Diana K S Nelson, BS, Kaitlin M Cruz, MD, Raphaëlle Klitting, PhD, Matthias G Pauthner, PhD, ProfPhD Kristian G Andersen, PhD, ProfPhD Jeffrey G Shaffer, PhD, Luis M Branco, PhD, ProfPhD Robert W Cross, PhD, ProfMD John S Schieffelin, PhD, ProfPhD Robert F Garry, PhD   +23 more
doaj   +1 more source

Chymase Level Is a Predictive Biomarker of Dengue Hemorrhagic Fever in Pediatric and Adult Patients

Journal of Infectious Diseases, 2017
Patients with acute dengue who present with high serum chymase levels are at greater risk of dengue hemorrhagic fever or dengue shock syndrome. The chymase level is a prognostic biomarker of severe dengue for adult and pediatric patients before they ...
H. Tissera, Abhay P. S. Rathore, W. Leong, B. Pike, T. Warkentien, Farouk S Farouk, A. Syenina, Eng Eong Ooi, D. Gubler, A. Wilder-Smith, A. S. St. John   +10 more
semanticscholar   +1 more source

Recent advances in understanding dengue [version 1; referees: 3 approved]

F1000Research, 2016
Dengue is an emerging threat to billions of people worldwide. In the last 20 years, the incidence has increased four-fold and this trend appears to be continuing.
Sophie Yacoub, Juthathip Mongkolsapaya, Gavin Screaton   +2 more
doaj   +1 more source

Dengue Hemorrhagic Fever: A State-of-the-Art Review Focused in Pulmonary Involvement

Lung, 2017
Dengue fever is an arboviral disease transmitted to humans through the bites of infected female Aedes mosquitoes. Dengue virus is a member of the Flaviviridae family, and human infection can be caused by any of the four antigenically distinct serotypes ...
Renata Rocha de Almeida, B. Paim, Solange Artimos de Oliveira, A. Souza, Antônio Carlos Portugal Gomes, D. Escuissato, G. Zanetti, E. Marchiori   +7 more
semanticscholar   +1 more source

The Current State of Vaccine Development for Specific Prophylactics of Arenaviral Hemorrhagic Fevers

Проблемы особо опасных инфекций, 2018
Presently, the Arenavirus genus (Arenaviridae family) includes 26 individual species of viruses. It is divided into two main groups – Old World arenaviruses and New World arenaviruses.
T. E. Sizikova, V. N. Lebedev, S. I. Syromyatnikova, S. V. Borisevich   +3 more
doaj   +1 more source

Global Epidemiology of Dengue Hemorrhagic Fever: An Update

, 2017
Although dengue was once a periodic disease that caused long-interval epidemics, today it is considered the most important mosquito-borne viral disease in the world [1].
A. Sanyaolu, C. Okorie, O. Badaru, Khadijat Adetona, M. Ahmed, O. Akanbi, Juanita Foncham, S. Kadavil, Lorena Likaj, Sarah Miraaj-Raza, Erika L. Pearce, Roberta Sylvester, Elizabeth Wallis   +12 more
semanticscholar   +1 more source

Hemorrhagic Fever with Renal Syndrome: Pathogenesis and Clinical Picture

Frontiers in Cellular and Infection Microbiology, 2016
Hantaan virus (HTNV) causes hemorrhagic fever with renal syndrome (HFRS), which is a zoonosis endemic in eastern Asia, especially in China. The reservoir host of HTNV is field mouse (Apodemus agraricus).
Hong Jiang, H. Du, Li M. Wang, Ping-zhong Wang, X. Bai   +4 more
semanticscholar   +1 more source

Analyis of changes in the serum concentration of cystatin c, creatinine and renal neutrophil gelatinase-associated lipocalin in patients with hemorrhagic fever with renal syndrome

Журнал инфектологии, 2015
Introduction. Acute kidney injury is a frequent complication of hemorrhagic fever with renal syndrome. The objective evaluation of аcute kidney injury severity degree is significant in determining the amount of medical actions at hemorrhagic fever with ...
E. M. Mingazova, D. A. Valishin, A. Z. Gilmanov, L. R. Shajhullina   +3 more
doaj   +1 more source

Seroepidemiological Studies of Crimean-Congo Hemorrhagic Fever Virus in Domestic and Wild Animals

PLoS Neglected Tropical Diseases, 2016
Crimean-Congo hemorrhagic fever (CCHF) is a widely distributed, tick-borne viral disease. Humans are the only species known to develop illness after CCHF virus (CCHFV) infection, characterized by a nonspecific febrile illness that can progress to severe,
J. Spengler, É. Bergeron, P. Rollin
semanticscholar   +1 more source