Results 31 to 40 of about 209,459 (341)

Calcium Prevents Enhanced Degradation of Factor VIII in the Condition of Motion

Biology, 2023
Background: Hemophilia A and B induce recurrent bleeding episodes, mainly in skeletal muscles and joints that are in intermittent motion. We have previously demonstrated that intermittent motion contributes to increased degradation of factors VIII and IX.
Haim Cohen, Anat Keren-Politansky, Yonatan Crispel, Chen Yanovich, Keren Asayag, Yona Nadir   +5 more
doaj   +1 more source

Recyclable Synthesis, Characterization, and Antimicrobial Activity of Chitosan-based Polysaccharide Composite Materials [PDF]

, 2013
We have successfully developed a simple and totally recyclable method to synthesize novel, biocompatible, and biodegradable composite materials from cellulose (CEL) and chitosan (CS).
Duri, Simon, Harkins, April, Tran, Chieu D.   +2 more
core   +2 more sources

Myricetin, the main flavonoid in Syzygium cumini leaf, is a novel inhibitor of platelet thiol isomerases PDI and ERp5 [PDF]

, 2020
Background: Flavonoids have been characterized as a prominent class of compounds to treat thrombotic diseases through the inhibition of thiol isomerases. Syzygium cumini is a flavonoid-rich medicinal plant that contains myricetin and gallic acid.
Ayyanar, Banno, Bekendam, Bi, Chagas, Chagas, Chang, Chen, Chung, Dang, De Bona, Dutta-Roy, Essex, Essex, Essex, Ghoshal, Giamogante, Giamogante, Holbrook, Inoue, Jarvis, Jasuja, Jayakumar, Jordan, Kang, Kehrel, Kim, Lahav, Lakowicz, Lescano, Lin, Lu, Mangin, Masuda, Navarro-Nuñez, Park, Raffaelli, Raturi, Sharma, Sousa, Stopa, Taylor, Trnkova, Wang, Ware, Wendelboe   +45 more
core   +1 more source

Hemostasis and nanotechnology [PDF]

Cardiovascular Diagnosis and Therapy, 2017
Hemorrhage accounts for significant morbidity and mortality. Various techniques have been employed to augment hemostasis from simple tourniquets to self-assembling nanoparticles. A growing understanding of the natural clotting cascade has allowed agents to become more targeted for potential use in different clinical scenarios.
Yu Shrike Zhang, Patrick T. Hangge, Rahmi Oklu, Jonathan J. Stone, Ali Khademhosseini, Hassan Albadawi   +5 more
openaire   +3 more sources

Hemostasis Strategies and Recent Advances in Nanomaterials for Hemostasis

Molecules, 2023
The development of materials that effectively stop bleeding and prevent wound adhesion is essential in both military and medical fields. However, traditional hemostasis methods, such as cautery, tourniquets, and gauze, have limitations. In recent years, new nanomaterials have gained popularity in medical and health fields due to their unique ...
Jian Du, Jingzhong Wang, Tao Xu, Hai Yao, Lili Yu, Da Huang   +5 more
openaire   +3 more sources

Effectiveness and Safety of Apixaban for Treatment of Venous Thromboembolism in Daily Practice

TH Open, 2020
Introduction Phase 3 trials have shown comparable efficacy of direct oral anticoagulants (DOACs) and vitamin K antagonists in patients with acute venous thromboembolism (VTE), with less major bleeding events in patients randomized to DOAC treatment. With
Stephan V. Hendriks, Frederikus A. Klok, Wilhelmina J.E. Stenger, Albert T.A. Mairuhu, Jeroen Eikenboom, Jaap Fogteloo, Menno V. Huisman   +6 more
doaj   +1 more source

The MHC Associated Peptide Proteomics assay is a useful tool for the non-clinical assessment of immunogenicity

Frontiers in Immunology, 2023
The propensity of therapeutic proteins to elicit an immune response, poses a significant challenge in clinical development and safety of the patients. Assessment of immunogenicity is crucial to predict potential adverse events and design safer biologics.
Wojciech Jankowski, Christopher Kidchob, Campbell Bunce, Edward Cloake, Ricardo Resende, Zuben E. Sauna   +5 more
doaj   +1 more source

History of the Innovation of Damage Control for Management of Trauma Patients: 1902-2016 [PDF]

, 2017
Objective: To review the history of the innovation of damage control (DC) for management of trauma patients. Background: DC is an important development in trauma care that provides a valuable case study in surgical innovation.
Ball, Chad G., Fabian, Timothy C., Feliciano, David V., Ivatury, Rao R., Kirkpatrick, Andrew W., Lucas, Charles E., Moore, Ernest E., Roberts, Derek J., Stelfox, Henry T., Zygun, David A.   +9 more
core   +3 more sources

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Von Willebrand Disease [PDF]

, 2017
Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
core   +2 more sources