Results 81 to 90 of about 133,701 (287)

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Dynamic, Reconfigurable, and Hierarchical Biosynthetic Composites via Collagen Self‐Assembly within Highly Crowded Microgel Pastes

Advanced Materials, EarlyView.
A new approach to extracellular matrix‐mimetic, hierarchical biomaterials is presented. Soft gels composed of overpacked hydrogel microparticle arrays present a biomolecularly crowded environment permissive to the self‐assembly of collagen networks.
Elif Narbay, Abbygail Caine, Sanika Pandit, Gabrielle Montgomery, Marion Harper, E. Daniel Cárdenas‐Vásquez, Hatte Hamilton, Megan Hicks, Daniel Mattar, Kyle Choy, Marco Bisoffi, L. Andrew Lyon   +11 more
wiley   +1 more source

Spider Silk–Integrated Biomimetic Micropillars With Dual Adhesion for Improved Wound Hemostasis and Healing

Advanced Materials Technologies, EarlyView.
The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan, Meng Wei, Xinran Chen, Ni Gan, Bingbing Gao   +4 more
wiley   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

Generation and pathogenicity of autoantibodies associated to thrombosis and hemostasis

Exploration of Immunology
Many acquired bleeding and thrombotic complications are provoked by autoantibodies to blood coagulation factors, or to hemostasis inhibitors and regulatory proteins.
Jean Amiral
doaj   +1 more source

EFFECT OF ANTICOAGULANT TREATMENT OF DABIGATRAN AND WARFARIN ON HEMOSTASIS IN PATIENTS WITH LIVER CIRRHOSIS AND ATRIAL FIBRILATION.

, 2022
A.E. Baylo, T.O. Maksymets, Vadym Shypulin, Volodymyr Chernyavskyi, L.M. Parunyan   +4 more
openalex   +2 more sources

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

Advanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen, Jingke Li, Yangyang Liu, Li Li, Xin Deng, Yilin Sheng, Xianyu Zhu, Xiao Jiang, Wei Li, Xueli Cai, Qiming Sun, Hu Hu   +11 more
wiley   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Tissue factor and hemostasis [published erratum appears in Blood 1988 Apr;71(4):1178] [PDF]

, 1988
Yale Nemerson
openalex   +1 more source