Results 91 to 100 of about 4,748 (186)
Characterization of functional human antibodies targeting henipavirus and flavivirus glycoproteins
, 2021 The henipaviruses Hendra (HeV) and Nipah (NiV), and the flavivirus yellow fever (YFV), pose massive global public health threats. No small molecule or antibody-based countermeasures are available to treat humans infected by HeV, NiV, or YFV, and major ...
Doyle, Michael Patrick
core
Emerging Microbes and InfectionsThe nuclear-cytoplasmic trafficking of matrix proteins (M) is essential for henipavirus budding, with M protein ubiquitination playing a pivotal role in this dynamic process.
Dongning Jin +12 more
doaj +1 more source
Paramyxo- and Coronaviruses in Rwandan Bats
Tropical Medicine and Infectious Disease, 2019 A high diversity of corona- and paramyxoviruses have been detected in different bat species at study sites worldwide, including Africa, however no biosurveillance studies from Rwanda have been reported.
Wanda Markotter +9 more
doaj +1 more source
Isolation and Full-Genome Characterization of Nipah Viruses from Bats, Bangladesh
Emerging Infectious Diseases, 2019 Despite molecular and serologic evidence of Nipah virus in bats from various locations, attempts to isolate live virus have been largely unsuccessful. We report isolation and full-genome characterization of 10 Nipah virus isolates from Pteropus medius ...
Danielle E. Anderson +13 more
doaj +1 more source
Animal Challenge Models of Henipavirus Infection and Pathogenesis [PDF]
, 2012 The henipaviruses, Hendra virus (HeV), and Nipah virus (NiV), are enigmatic emerging pathogens that causes severe and often fatal neurologic and/or respiratory disease in both animals and humans. Amongst people, case fatality rates range between 40 and 75% and there are no vaccines or treatments approved for human use.
Geisbert, Thomas W. +2 more
openaire +2 more sources
Henipavirus and Tioman Virus Antibodies in Pteropodid Bats, Madagascar
Emerging Infectious Diseases, 2007 Specimens were obtained from the 3 Malagasy fruit bats, Pteropus rufus, Eidolon dupreanum, and Rousettus madagascariensis. Antibodies against Nipah, Hendra, and Tioman viruses were detected by immunoassay in 23 and by serum neutralization tests in 3 of ...
Catherine Iehlé +7 more
doaj +1 more source
Cross-protectivity of henipavirus soluble glycoprotein in an <i>in vivo</i> model of Nipah virus disease. [PDF]
Front ImmunolIntroduction: Nipah virus (NiV) is one of a group of highly pathogenic viruses classified within the Henipavirus genus. Since 2012 at least 11 new henipa-like viruses have been identified, including from new locations and reservoir hosts; the ...
Findlay-Wilson S +9 more
europepmc +2 more sources
Henipavirus-related Sequences in Fruit Bat Bushmeat, Republic of Congo [PDF]
, 2012 TO THE EDITOR: Bats are hosts for various emerging viruses, including the zoonotic paramyxoviruses Hendra virus and Nipah virus, which occur in Australia and Southeast Asia, respectively, and cause severe disease outbreaks among humans and livestock (1).
Mombouli, J. +26 more
core +1 more source
Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination
VirusesHendra virus (HeV) is a highly pathogenic member of the Henipavirus genus (family Paramyxoviridae, order Mononegavirales), for which all basic replication processes are located in the cytoplasm.
Tianyue Zhao +6 more
doaj +1 more source
Characterization of an mRNA-Encoded Antibody Against Henipavirus
Current Issues in Molecular BiologyNipah and Hendra viruses are lethal zoonotic pathogens with no approved vaccines or therapeutics. mRNA produced via in vitro transcription enables endogenous protein expression and cost reduction.
Zixuan Liu +9 more
doaj +1 more source