Results 91 to 100 of about 4,949 (186)

Modulation of the interferon response during henipavirus infection

open access: yes, 2011
© 2011 Dr. Elena R. VirtueHendra and Nipah viruses, members of the genus Henipavirus within the family Paramyxoviridae, cause lethal infection in humans and animals. The exact mechanism of pathogenesis for these viruses is unknown.
Virtue, Elena R.
core   +1 more source

Genetic Characterization of Nipah Virus, Bangladesh, 2004

open access: yesEmerging Infectious Diseases, 2005
Until 2004, identification of Nipah virus (NV)-like outbreaks in Bangladesh was based on serology. We describe the genetic characterization of a new strain of NV isolated during outbreaks in Bangladesh (NV-B) in 2004, which confirms that NV was the ...
Brian H. Harcourt   +13 more
doaj   +1 more source

The E3 ligase RAD18-mediated ubiquitination of henipavirus matrix protein promotes its nuclear-cytoplasmic trafficking and viral egress

open access: yesEmerging Microbes and Infections
The nuclear-cytoplasmic trafficking of matrix proteins (M) is essential for henipavirus budding, with M protein ubiquitination playing a pivotal role in this dynamic process.
Dongning Jin   +12 more
doaj   +1 more source

Paramyxo- and Coronaviruses in Rwandan Bats

open access: yesTropical Medicine and Infectious Disease, 2019
A high diversity of corona- and paramyxoviruses have been detected in different bat species at study sites worldwide, including Africa, however no biosurveillance studies from Rwanda have been reported.
Wanda Markotter   +9 more
doaj   +1 more source

A Functional Genomics Approach to Henipavirus Research: The Role of Nuclear Proteins, MicroRNAs and Immune Regulators in Infection and Disease.

open access: yes, 2018
Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are zoonotic RNA viruses that cause lethal disease in humans and are designated as Biosafety Level 4 (BSL4) agents.
Deffrasnes, C   +4 more
core   +1 more source

Isolation and Full-Genome Characterization of Nipah Viruses from Bats, Bangladesh

open access: yesEmerging Infectious Diseases, 2019
Despite molecular and serologic evidence of Nipah virus in bats from various locations, attempts to isolate live virus have been largely unsuccessful. We report isolation and full-genome characterization of 10 Nipah virus isolates from Pteropus medius ...
Danielle E. Anderson   +13 more
doaj   +1 more source

Characterization of functional human antibodies targeting henipavirus and flavivirus glycoproteins

open access: yes, 2021
The henipaviruses Hendra (HeV) and Nipah (NiV), and the flavivirus yellow fever (YFV), pose massive global public health threats. No small molecule or antibody-based countermeasures are available to treat humans infected by HeV, NiV, or YFV, and major ...
Doyle, Michael Patrick
core  

Henipavirus and Tioman Virus Antibodies in Pteropodid Bats, Madagascar

open access: yesEmerging Infectious Diseases, 2007
Specimens were obtained from the 3 Malagasy fruit bats, Pteropus rufus, Eidolon dupreanum, and Rousettus madagascariensis. Antibodies against Nipah, Hendra, and Tioman viruses were detected by immunoassay in 23 and by serum neutralization tests in 3 of ...
Catherine Iehlé   +7 more
doaj   +1 more source

Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination

open access: yesViruses
Hendra virus (HeV) is a highly pathogenic member of the Henipavirus genus (family Paramyxoviridae, order Mononegavirales), for which all basic replication processes are located in the cytoplasm.
Tianyue Zhao   +6 more
doaj   +1 more source

Characterization of an mRNA-Encoded Antibody Against Henipavirus

open access: yesCurrent Issues in Molecular Biology
Nipah and Hendra viruses are lethal zoonotic pathogens with no approved vaccines or therapeutics. mRNA produced via in vitro transcription enables endogenous protein expression and cost reduction.
Zixuan Liu   +9 more
doaj   +1 more source

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