Results 71 to 80 of about 5,865 (207)

High Pathogenicity of Nipah Virus from Pteropus lylei Fruit Bats, Cambodia

open access: yesEmerging Infectious Diseases, 2020
We conducted an in-depth characterization of the Nipah virus (NiV) isolate previously obtained from a Pteropus lylei bat in Cambodia in 2003 (CSUR381). We performed full-genome sequencing and phylogenetic analyses and confirmed CSUR381 is part of the NiV-
Maria Gaudino   +10 more
doaj   +1 more source

Mapping the Potential Risk of Coronavirus Spillovers in a Global Hotspot

open access: yesGlobal Change Biology, Volume 31, Issue 9, September 2025.
Bats host a vast array of viruses, including those behind SARS and COVID‐19. This study maps coronavirus spillover risk hotspots across South and Southeast Asia by combining horseshoe bat species distributions, forest fragmentation, and human population density.
R. Sedricke Lapuz   +2 more
wiley   +1 more source

Henipavirus: A Review of Laboratory Animal Pathology [PDF]

open access: yesVeterinary Pathology, 2010
The genus Henipavirus contains two members—Hendra virus (HeV) and Nipah virus (NiV)—and each can cause fatal disease in humans and animals. HeV and Niv are currently classified as biosafety level 4, and NiV is classified as a category C priority pathogen.
M M, Williamson, F J, Torres-Velez
openaire   +2 more sources

Differential Features of Fusion Activation within the Paramyxoviridae

open access: yesViruses, 2020
Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated.
Kristopher D. Azarm, Benhur Lee
doaj   +1 more source

Envelope-receptor interactions in Nipah virus pathobiology. [PDF]

open access: yes, 2007
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core   +1 more source

Nipah shell disorder, modes of infection, and virulence [PDF]

open access: yes, 2020
The Nipah Virus (NiV) was first isolated during a 1998–9 outbreak in Malaysia. The outbreak initially infected farm pigs and then moved to humans from pigs with a case-fatality rate (CFR) of about 40%.
Dunker, A. Keith   +3 more
core   +1 more source

Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein

open access: yesAdvanced Science, Volume 12, Issue 27, July 17, 2025.
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren   +19 more
wiley   +1 more source

From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis

open access: yesMicrobial Biotechnology, Volume 18, Issue 7, July 2025.
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley   +1 more source

Nipah Virus Efficiently Replicates in Human Smooth Muscle Cells without Cytopathic Effect

open access: yesCells, 2021
Nipah virus (NiV) is a highly pathogenic zoonotic virus with a broad species tropism, originating in pteropid bats. Human outbreaks of NiV disease occur almost annually, often with high case-fatality rates.
Blair L. DeBuysscher   +5 more
doaj   +1 more source

Land Use Change and Infectious Disease Emergence

open access: yesReviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli   +6 more
wiley   +1 more source

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