Results 71 to 80 of about 4,748 (186)

Interferon Signaling Remains Functional during Henipavirus Infection of Human Cell Lines

open access: yes, 2011
Henipaviruses encode several proteins from the P gene, of which V and W have been demonstrated by gene-based transfection studies to antagonize the innate immune response, blocking both type I interferon production and signaling.
Elena R. Virtue   +2 more
core   +1 more source

Land Use Change and Infectious Disease Emergence

open access: yesReviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli   +6 more
wiley   +1 more source

Pathogenicity of Nipah henipavirus Bangladesh in a swine host [PDF]

open access: yesScientific Reports, 2019
Abstract In 1998 an outbreak of fatal encephalitis among pig farm workers in Malaysia and Singapore led to the discovery of Nipah henipavirus (NiV), a novel paramyxovirus closely related to Hendra henipavirus with case fatality rates of nearly 40%.
Kasloff, S. B.   +8 more
openaire   +2 more sources

Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain

open access: yesProtein Science, Volume 34, Issue 3, March 2025.
Abstract Hendra virus (HeV) is a biosafety level 4 human pathogen belonging to the Henipavirus genus within the Paramyxoviridae family. In HeV, the phosphoprotein‐encoding gene also drives the synthesis of the V and W proteins that are two major players in the host innate immune response evasion.
Frank Gondelaud   +8 more
wiley   +1 more source

Henipavirus neutralising antibodies in an isolated island population of African fruit bats. [PDF]

open access: yes, 2012
Isolated islands provide valuable opportunities to study the persistence of viruses in wildlife populations, including population size thresholds such as the critical community size.
Peel, A.J.   +67 more
core   +1 more source

Hendra Virus Outbreak with Novel Clinical Features, Australia

open access: yesEmerging Infectious Diseases, 2010
To determine the epidemiologic and clinical features of a 2008 outbreak of Hendra virus infection in a veterinary clinic in Australia, we investigated the equine case-series. Four of 5 infected horses died, as did 1 of 2 infected staff members.
Hume E. Field   +12 more
doaj   +1 more source

Emerging Nipah Virus With Pandemic Potential and High Mortality Rates: Is the Scientific Community Learning From Former Pandemics?

open access: yesReviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT As Nipah virus (NiV) infection is characterised by a possible pandemic risk, being currently limited to a small but deadly belt, the attention of other countries is essential. It has often been pointed out that NiV is an under‐researched virus with a high‐risk potential. This study aimed to show the global research history and status quo based
Doris Klingelhöfer   +4 more
wiley   +1 more source

Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N‐ and C‐terminal constituent domains

open access: yesThe FEBS Journal, Volume 292, Issue 3, Page 556-581, February 2025.
The W proteins of Nipah and Hendra viruses exhibit fibrillation abilities in vitro, which have been attributed to the intrinsically disordered N‐terminal domain (NTD). Our research shows that the C‐terminal domain (CTD) of both viruses is intrinsically disordered and non‐fibrillogenic.
Giulia Pesce   +5 more
wiley   +1 more source

Influence of Host and Landscape‐Associated Factors in the Infection and Transmission of Pathogens: The Case of Directly Transmitted Virus in Mammals

open access: yesVeterinary Medicine and Science, Volume 11, Issue 1, January 2025.
The figure shows the effects (increasing upward arrow or decreasing downward arrow) the most common host traits, landscape attributes, climatic features and anthropogenic variables recorded in the review had on the infection and transmission of directly transmitted virus to mammals.
María del Carmen Villalobos‐Segura   +3 more
wiley   +1 more source

The Emergence of Novel Langya Henipavirus in China

open access: yes, 2022
In August 2022, a research study in China reported the emergence of Langya henipavirus (LayV), a novel zoonotic henipavirus. LayV had infected 35 people in Shandong and Henan provinces between 2018 – 2021, with shrews suspected to be the natural ...
Rosalie Chen, Ashley Quigley
core   +1 more source

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