Results 61 to 70 of about 4,748 (186)
Integrating host condition into spatiotemporal multiscale models improves virus shedding predictions
Understanding where and when pathogens occur in the environment has implications for reservoir population health and infection risk. In reservoir hosts, infection status and pathogen shedding are affected by processes interacting across different scales: from landscape features affecting host location and transmission to within‐host processes affecting
Andrew M. Kramer +9 more
wiley +1 more source
LANGYA: A NEW HENIPAVIRUS IN CHINA
China once again has a new virus outbreak which may be a Global health issue. First case of LayV) in human was reported on 8 August 2022, total 35 cases were reported. This may be a global health issue as like Covid 19.
CHAVAN, GITANJALI +2 more
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High Pathogenicity of Nipah Virus from Pteropus lylei Fruit Bats, Cambodia
We conducted an in-depth characterization of the Nipah virus (NiV) isolate previously obtained from a Pteropus lylei bat in Cambodia in 2003 (CSUR381). We performed full-genome sequencing and phylogenetic analyses and confirmed CSUR381 is part of the NiV-
Maria Gaudino +10 more
doaj +1 more source
Mapping the Potential Risk of Coronavirus Spillovers in a Global Hotspot
Bats host a vast array of viruses, including those behind SARS and COVID‐19. This study maps coronavirus spillover risk hotspots across South and Southeast Asia by combining horseshoe bat species distributions, forest fragmentation, and human population density.
R. Sedricke Lapuz +2 more
wiley +1 more source
Forscher entdecken in China neues Henipavirus
In China sind 35 Menschen an einem neu nachgewiesenen Henipavirus erkrankt, das wahrscheinlich von einem Tier stammt. Die Infektionen mit dem Langya-Henipavirus (LayV) benannten Erreger traten in den Provinzen Shangdong und Henan vor allem bei Farmern ...
Deutsche Presseagentur. Archiv
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Differential Features of Fusion Activation within the Paramyxoviridae
Paramyxovirus (PMV) entry requires the coordinated action of two envelope glycoproteins, the receptor binding protein (RBP) and fusion protein (F). The sequence of events that occurs during the PMV entry process is tightly regulated.
Kristopher D. Azarm, Benhur Lee
doaj +1 more source
Potent Cross‐neutralizing Antibodies Reveal Vulnerabilities of Henipavirus Fusion Glycoprotein
Hendra and Nipah viruses (HNVs) pose significant threats to global health. This work reports potent cross‐neutralizing antibodies targeting the fusion glycoprotein (F) and reveals shared features of these antibodies and vulnerabilities of F, thereby guiding the rational design of countermeasures against HNVs and similar pathogens.
Yi Ren +19 more
wiley +1 more source
From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley +1 more source
Henipavirus Vaccine Development
The henipaviruses, Hendra virus and Nipah virus, belong to the family Paramyxoviridae which has long been a source of highly contagious pathogens for both humans and animals. Some notable paramyxoviruses such as measles virus have spilled over from animals into humans to cause significant morbidity and mortality.
Jackie Pallister +2 more
openaire +1 more source
Nipah Virus Efficiently Replicates in Human Smooth Muscle Cells without Cytopathic Effect
Nipah virus (NiV) is a highly pathogenic zoonotic virus with a broad species tropism, originating in pteropid bats. Human outbreaks of NiV disease occur almost annually, often with high case-fatality rates.
Blair L. DeBuysscher +5 more
doaj +1 more source

