Rhabdovirus-based vaccine platforms against henipaviruses. [PDF]
UNLABELLED: The emerging zoonotic pathogens Hendra virus (HeV) and Nipah virus (NiV) are in the genus Henipavirus in the family Paramyxoviridae. HeV and NiV infections can be highly fatal to humans and livestock.
Feldmann, Heinz +4 more
core +2 more sources
Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P +3 more
core +1 more source
Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. [PDF]
Nipah virus (NiV) is a paramyxovirus that infects host cells through the coordinated efforts of two envelope glycoproteins. The G glycoprotein attaches to cell receptors, triggering the fusion (F) glycoprotein to execute membrane fusion.
Aguilar, Hector C +14 more
core +2 more sources
Seasonal shedding patterns of diverse henipavirus-related paramyxoviruses in Egyptian rousette bats
Bat-borne viruses in the Henipavirus genus have been associated with zoonotic diseases of high morbidity and mortality in Asia and Australia. In Africa, the Egyptian rousette bat species (Rousettus aegyptiacus) is an important viral host in which ...
Marinda Mortlock +6 more
doaj +1 more source
The henipaviruses, Nipah virus (NiV), and Hendra virus (HeV) can cause fatal diseases in humans and animals, whereas Cedar virus is a nonpathogenic henipavirus.
Moushimi Amaya +12 more
doaj +1 more source
A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus. [PDF]
Abstract The Hendra (HeV) and Nipah (NiV) viruses are high‐priority, biosafety level‐4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essential polymerase cofactor, but also the virulence factors V and W.
Gondelaud F +4 more
europepmc +2 more sources
Antiviral activity of gliotoxin, gentian violet and brilliant green against Nipah and Hendra virus in vitro [PDF]
Background: Using a recently described monolayer assay amenable to high throughput screening format for the identification of potential Nipah virus and Hendra virus antivirals, we have partially screened a low molecular weight compound library (8,000 ...
Mohamad Aljofan +8 more
core +1 more source
A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus
An expanded hydrophobic cavity within the structurally constrained receptor-binding site of the Cedar virus attachment glycoprotein facilitates idiosyncratic utilization of ephrin-B1. The emergent zoonotic henipaviruses, Hendra, and Nipah are responsible
Rhys Pryce +5 more
doaj +1 more source
Hendra and Nipah virus infection in cultured human olfactory epithelial cells [PDF]
Henipaviruses are emerging zoonotic viruses and causative agents of encephalitis in humans. However, the mechanisms of entry into the central nervous system (CNS) in humans are not known.
Barry Rockx +4 more
core +4 more sources
Background: An outbreak of the rare and highly pathogenic Nipah virus infection occurred in Kozhikode, Kerala, India, during May 2018. Methodology: Outbreak control activities included laboratory case confirmation and isolation.
Bina Thomas +10 more
doaj +1 more source

