Support for viral persistence in bats from age-specific serology and models of maternal immunity. [PDF]
, 2018 Spatiotemporally-localised prediction of virus emergence from wildlife requires focused studies on the ecology and immunology of reservoir hosts in their native habitat.
Baker, Kate S +8 more
core +4 more sources
Subclinical infection without encephalitis in mice following intranasal exposure to Nipah virus-Malaysia and Nipah virus-Bangladesh [PDF]
, 2014 BACKGROUND: Nipah virus and Hendra virus are closely related and following natural or experimental exposure induce similar clinical disease. In humans, encephalitis is the most serious outcome of infection and, hitherto, research into the pathogenesis of
Deborah Middleton +5 more
core +1 more source
Henipavirus Mediated Membrane Fusion, Virus Entry and Targeted Therapeutics
Viruses, 2012 The Paramyxoviridae genus Henipavirus is presently represented by the type species Hendra and Nipah viruses which are both recently emerged zoonotic viral pathogens responsible for repeated outbreaks associated with high morbidity and mortality in ...
Dimitar B. Nikolov +3 more
doaj +1 more source
Monomeric ephrinB2 binding induces allosteric changes in Nipah virus G that precede its full activation. [PDF]
, 2017 Nipah virus is an emergent paramyxovirus that causes deadly encephalitis and respiratory infections in humans. Two glycoproteins coordinate the infection of host cells, an attachment protein (G), which binds to cell surface receptors, and a fusion (F ...
Jardetzky, Theodore S +9 more
core +2 more sources
The YPLGVG sequence of the Nipah virus matrix protein is required for budding [PDF]
, 2008 Background Nipah virus (NiV) is a recently emerged paramyxovirus capable of causing fatal disease in a broad range of mammalian hosts, including humans.
Yan Lianying +6 more
core +2 more sources
Henipavirus Receptor Usage and Tropism [PDF]
, 2012 Nipah (NiV) and Hendra (HeV) viruses are the deadliest human pathogens within the Paramyxoviridae family, which include human and animal pathogens of global biomedical importance. NiV and HeV infections cause respiratory and encephalitic illness with high mortality rates in humans.
Olivier, Pernet +2 more
openaire +2 more sources
Drivers and Distribution of Henipavirus-Induced Syncytia: What Do We Know?
Viruses, 2021 Syncytium formation, i.e., cell–cell fusion resulting in the formation of multinucleated cells, is a hallmark of infection by paramyxoviruses and other pathogenic viruses. This natural mechanism has historically been a diagnostic marker for paramyxovirus
Amandine Gamble +9 more
doaj +1 more source
Henipavirus-induced neuropathogenesis in mice
Virology, 2023 Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses that can cause fatal encephalitis in humans. Many animal models have been used to study henipavirus pathogenesis. In the mouse, HeV infection has previously shown that intranasal challenge can lead to neurological infection, however mice similarly challenged with NiV show no evidence of virus ...
Sarah J. Edwards +8 more
openaire +2 more sources
Nipah@20: Lessons Learned from Another Virus with Pandemic Potential
mSphere, 2020 Nipah disease is listed as one of the WHO priority diseases that pose the greatest public health risk due to their epidemic potential. More than 200 experts from around the world convened in Singapore last year to mark the 20th anniversary of the first ...
Raúl Gómez Román +8 more
doaj +3 more sources
Clinical perspectives of emerging pathogens in bleeding disorders. [PDF]
, 2006 As a result of immunological and nucleic-acid screening of plasma donations for transfusion-transmissible viruses, and the incorporation of viral reduction processes during plasma fractionation, coagulation-factor concentrates (CFC) are now judged safe ...
Bozzette, Samuel +11 more
core +5 more sources