Outbreak of Henipavirus Infection, Philippines, 2014
Emerging Infectious Diseases, 2015 During 2014, henipavirus infection caused severe illness among humans and horses in southern Philippines; fatality rates among humans were high. Horse-to-human and human-to-human transmission occurred.
Paola Katrina G. Ching +16 more
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Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains [PDF]
PLoS Neglected Tropical Diseases, 2018 Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide gene
Alberto J Leon +2 more
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Henipavirus Mediated Membrane Fusion, Virus Entry and Targeted Therapeutics
Viruses, 2012 The Paramyxoviridae genus Henipavirus is presently represented by the type species Hendra and Nipah viruses which are both recently emerged zoonotic viral pathogens responsible for repeated outbreaks associated with high morbidity and mortality in ...
Dimitar B. Nikolov +3 more
doaj +2 more sources
Henipavirus: A Review of Laboratory Animal Pathology [PDF]
Veterinary Pathology, 2010 The genus Henipavirus contains two members—Hendra virus (HeV) and Nipah virus (NiV)—and each can cause fatal disease in humans and animals. HeV and Niv are currently classified as biosafety level 4, and NiV is classified as a category C priority pathogen.
M M, Williamson, F J, Torres-Velez
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Henipavirus sero-surveillance in horses and pigs from Northern Nigeria [PDF]
Frontiers in Virology, 2022 Hendra virus and Nipah virus are considered to be emerging viruses and cause severe zoonotic diseases, which occur in humans who have had close contact with horses and pigs in Australia and Asia, respectively. Both viruses belong to the genus Henipavirus.
Andrew Musa Adamu +11 more
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Dual microRNA Screens Reveal That the Immune-Responsive miR-181 Promotes Henipavirus Entry and Cell-Cell Fusion. [PDF]
PLoS Pathogens, 2016 Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are bat-borne viruses that cause fatal disease in humans and a range of other mammalian species. Gaining a deeper understanding of host pathways exploited by henipaviruses for infection
Chwan Hong Foo +13 more
doaj +3 more sources
Ecological and Reproductive Cycles Drive Henipavirus Seroprevalence in the African Straw‐Coloured Fruit Bat (Eidolon helvum) [PDF]
Ecology and EvolutionBats are known to host zoonotic viruses, including henipaviruses that cause high fatality rates in humans (Nipah virus and Hendra virus). However, the determinants of zoonotic spillover are generally unknown, as the ecological and demographic drivers of ...
Maya M. Juman +15 more
doaj +6 more sources
Heparan Sulfate-Dependent Enhancement of Henipavirus Infection [PDF]
mBio, 2015 ABSTRACT Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus . They infect humans as well as numerous mammalian species. Both viruses use ephrin-B2 and -B3 as cell entry receptors, and following initial entry into an organism, they are
Mathieu, Cyrille +9 more
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Drivers and Distribution of Henipavirus-Induced Syncytia: What Do We Know?
Viruses, 2021 Syncytium formation, i.e., cell–cell fusion resulting in the formation of multinucleated cells, is a hallmark of infection by paramyxoviruses and other pathogenic viruses. This natural mechanism has historically been a diagnostic marker for paramyxovirus
Amandine Gamble +2 more
exaly +3 more sources
A Functional
Virology Journal, 2010 Background Hendra virus (HeV) and Nipah virus (NiV) are newly emerged zoonotic paramyxoviruses discovered during outbreaks in Queensland, Australia in 1994 and peninsular Malaysia in 1998/9 respectively and classified within the new Henipavirus genus ...
Broder Christopher C, Khetawat Dimple
doaj +2 more sources