Results 21 to 30 of about 4,949 (186)

Heparan Sulfate-Dependent Enhancement of Henipavirus Infection [PDF]

mBio, 2015
ABSTRACT Nipah virus and Hendra virus are emerging, highly pathogenic, zoonotic paramyxoviruses that belong to the genus Henipavirus . They infect humans as well as numerous mammalian species. Both viruses use ephrin-B2 and -B3 as cell entry receptors, and following initial entry into an organism, they are
Mathieu, Cyrille, Dhondt, Kévin P, Châlons, Marie, Mély, Stéphane, Raoul, Hervé, Negre, Didier, François-Loïc, Cosset, Gerlier, Denis, Vivès, Romain R, Horvat, Branka   +9 more
openaire   +5 more sources

Host gene expression profiles in ferrets infected with genetically distinct henipavirus strains. [PDF]

PLoS Neglected Tropical Diseases, 2018
Henipavirus infection causes severe respiratory and neurological disease in humans that can be fatal. To characterize the pathogenic mechanisms of henipavirus infection in vivo, we performed experimental infections in ferrets followed by genome-wide gene
Alberto J Leon, Viktoriya Borisevich, Nahal Boroumand, Robert Seymour, Rebecca Nusbaum, Olivier Escaffre, Luoling Xu, David J Kelvin, Barry Rockx   +8 more
doaj   +4 more sources

A Functional Henipavirus Envelope Glycoprotein Pseudotyped Lentivirus Assay System [PDF]

Virology Journal, 2010
Background Hendra virus (HeV) and Nipah virus (NiV) are newly emerged zoonotic paramyxoviruses discovered during outbreaks in Queensland, Australia in 1994 and peninsular Malaysia in 1998/9 respectively and classified within the new Henipavirus genus ...
Broder Christopher C, Khetawat Dimple
doaj   +2 more sources

Integrating Prevention and Response at the Crossroads of Henipavirus Preparedness, Hendra@30 Conference, 2024 [PDF]

Emerging Infectious Diseases
Diseases caused by henipaviruses, exemplified by Hendra virus and Nipah virus, pose a serious risk to public health because of their epidemic potential and high case-fatality rates and the paucity of medical countermeasures to mitigate them. In December
Kim Halpin, Raúl Gómez Román, Emmie de Wit, Alison J. Peel, Jonathan H. Epstein, Jennifer Barr, Sarah J. Edwards, Melanie N. Tripp, Berta Blanch-Lázaro, Belinda Linnegar, Gervais Habarugira, Glenn A. Marsh, Danielle Anderson, Li-Yen Chang, Wanda Markotter   +14 more
doaj   +2 more sources

Nipah Virus Antibodies in Bats, the Philippines, 2013–2022 [PDF]

Emerging Infectious Diseases
In 2014, an outbreak of zoonotic Nipah virus (NiV) occurred on Mindanao Island, the Philippines. We investigated the prevalence of NiV in Philippine bats.
Yoshihiro Kaku, Shumpei Watanabe, Joseph S. Masangkay, Phillip Alviola, Satoshi Taniguchi, Edison Cosico, Yumi Une, Frances C. Recuenco, Satoko Sugimoto, Kentaro Kato, Shigeru Kyuwa, David Emmanuel M. General, Allen John F. Manalad, Sheryl A. Yap, Hironori Bando, Nanako Isobe, Yui Sakata, Shione Takeguchi, Hikaru Fujii, Masayuki Shimojima, Shigeru Morikawa, Ken Maeda, Tsutomu Omatsu   +22 more
doaj   +2 more sources

The intracellular virus-host interface of henipaviruses [PDF]

Journal of Virology
The Henipavirus genus comprises five viral species, of which the prototype members, Hendra virus (HeV) and Nipah virus (NiV), are reported to infect humans.
Melanie N. Tripp, Stephen M. Rawlinson, Sarah J. Edwards, Jasmina M. Luczo, Glenn A. Marsh, Kim Halpin, Gregory W. Moseley   +6 more
doaj   +2 more sources

A conserved motif in Henipavirus P/V/W proteins drives the fibrillation of the W protein from Hendra virus

Protein Science, Volume 34, Issue 4, April 2025.
Abstract The Hendra (HeV) and Nipah (NiV) viruses are high‐priority, biosafety level‐4 pathogens that cause fatal neurological and respiratory disease. Their P gene encodes not only the P protein, an essential polymerase cofactor, but also the virulence factors V and W.
Frank Gondelaud, Christophe Bignon, Denis Ptchelkine, Frédéric Carrière, Sonia Longhi   +4 more
wiley   +2 more sources

A recombinant Cedar virus preclinical model that recapitulates neurological features of henipavirus disease [PDF]

iScience
Summary: Nipah virus (NiV) and Hendra virus (HeV) are members of the henipavirus genus that cause severe respiratory and/or neurological disease in humans.
Celeste Huaman, Caitlyn Clouse, Madeline Rader, Allison M. Strazzella, Jocelyn King, Elise M. Santorella, Lianying Yan, Shuangyi Bai, Bronwyn M. Gunn, Moushimi Amaya, Christopher C. Broder, Brian C. Schaefer   +11 more
doaj   +2 more sources

Genetic Diversity and Geographic Spread of Henipaviruses [PDF]

Emerging Infectious Diseases
Henipaviruses, such as Hendra and Nipah viruses, are major zoonotic pathogens that cause encephalitis and respiratory infections in humans and animals.
Yakhouba Kane, Betty Nalikka, Alexander Tendu, Victor Omondi, Kathrina Mae Bienes, Abdou Padane, Veasna Duong, Nicolas Berthet, Gary Wong   +8 more
doaj   +2 more sources

An in silico approach for structural and functional annotation of matrix protein of Nipah henipavirus: A protein functional analysis [PDF]

, 2021
Nipah henipavirus is an emerging RNA virus with increased mortality threatening global security. In South and Southeast Asia, the Nipah virus has caused numerous disease outbreaks.
Apurbo Kumar, Paul, Abu Saim Mohammad , Saikat   +1 more
core   +1 more source