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Recombinant Soluble Henipavirus Glycoprotein Preparation
2023Henipaviruses possess two envelope glycoproteins, the attachment (G) and the fusion (F) proteins that mediate cellular entry and are the major targets of virus-neutralizing antibody responses. Recombinant expression technologies have been used to produce soluble G and F proteins (sG and sF) that retain native-like oligomeric conformations and epitopes,
Lianying, Yan +6 more
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Animal models of henipavirus infection: A review
The Veterinary Journal, 2009Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level four pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
Hana M, Weingartl +2 more
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Infection and transmission of henipavirus in animals
Comparative Immunology, Microbiology and Infectious DiseasesHenipavirus (HNV) is well known for two zoonotic viruses in the genus, Hendra virus (HeV) and Nipah virus (NiV), which pose serious threat to human and animal health. In August 2022, a third zoonotic virus in the genus Henipavirus, Langya virus (LayV), was discovered in China.
Xinyu Qiu, Feng Wang, Ailong Sha
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Henipavirus Membrane Fusion and Viral Entry
2012Nipah (NiV) and Hendra (HeV) viruses cause cell-cell fusion (syncytia) in brain, lung, heart, and kidney tissues, leading to encephalitis, pneumonia, and often death. Membrane fusion is essential to both viral entry and virus-induced cell-cell fusion, a hallmark of henipavirus infections.
Hector C, Aguilar, Ronald M, Iorio
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Current Status of Diagnostic Methods for Henipavirus
2013Hendra virus (HeV) and Nipah virus (NiV) are the causative agents of emerging transboundary animal disease in pigs and horses. They also cause fatal disease in humans. NiV has a case fatality rate of 40 - 100%. In the initial NiV outbreak in Malaysia in 1999, about 1.1 million pigs had to be culled. The economic impact was estimated to be approximately
A, Tamin, P A, Rota
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A Zoonotic Henipavirus in Febrile Patients in China
New England Journal of Medicine, 2022Xiao-Ai Zhang +16 more
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The Structural Features of Henipavirus Matrix Protein Driving Intracellular Trafficking
Viral Immunology, 2021Shane Raidal +2 more
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A Survey of Henipavirus Tropism—Our Current Understanding from a Species/Organ and Cellular Level
Viruses, 2023Sandra Diederich +2 more
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