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Structural biology of Nipah virus G and F glycoproteins: Insights into therapeutic and vaccine development. [PDF]
Eur J Microbiol Immunol (Bp)Salleh MZ.
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Pseudotyped Virus for Henipavirus
2023The genus Henipavirus (HNV) includes two virulent infectious viruses, Nipah virus (NiV) and Hendra virus (HeV), which are the focus of considerable public health research efforts and have been classified as priority infectious diseases by the World Health Organization.
Tao, Li +3 more
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Zoonotic henipavirus transmission
Journal of Clinical Virology, 2013Funding. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 355 Competing interests . . . . . . . . . . . . . . . . .
Barry, Rockx, Lin-Fa, Wang
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Assays for Detecting Henipavirus Antibodies
2023While molecular detection has increasingly become the detection method of choice for infectious diseases, antibody detection remains an important approach for diagnosis and surveillance. For henipaviruses, antibody detection methods such as ELISA and Western blot played a key role in the initial discovery of bats as the natural reservoir host. Here, we
Lin-Fa, Wang +3 more
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Ferret Models for Henipavirus Infection
2023Henipaviruses are emerging zoonotic viruses that can cause outbreaks of severe respiratory and neurological disease in humans and animals such as horses. The mechanism by which these viruses can cause disease remain largely unknown and to date there are no therapeutics or vaccines approved for use in humans.
Rockx, Barry, Mire, Chad E.
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Henipavirus pathogenesis and antiviral approaches
Expert Review of Anti-infective Therapy, 2015Hendra virus and Nipah virus are closely related, recently emerged zoonotic paramyxoviruses, belonging to the Henipavirus genus. Both viruses induce generalized vasculitis affecting particularly the respiratory tract and CNS. The exceptionally broad species tropism of Henipavirus, the high case fatality rate and person-to-person transmission associated
Mathieu, Cyrille, Horvat, Branka
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Mouse Models of Henipavirus Infection
2023The Nipah and Hendra viruses, belonging to henipavirus genus, are recently emerged zoonotic pathogens that cause severe and often fatal, neurologic, and/or respiratory diseases in both humans and various animals. As mice represent a small animal model convenient to study viral infections and provide a well-developed experimental toolbox for analysis in
Iampietro, Mathieu +3 more
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Recombinant Soluble Henipavirus Glycoprotein Preparation
2023Henipaviruses possess two envelope glycoproteins, the attachment (G) and the fusion (F) proteins that mediate cellular entry and are the major targets of virus-neutralizing antibody responses. Recombinant expression technologies have been used to produce soluble G and F proteins (sG and sF) that retain native-like oligomeric conformations and epitopes,
Lianying, Yan +6 more
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Recent progress in henipavirus research
Comparative Immunology, Microbiology and Infectious Diseases, 2007Following the discovery of two new paramyxoviruses in the 1990s, much effort has been placed on rapidly finding the reservoir hosts, characterising the genomes, identifying the viral receptors and formulating potential vaccines and therapeutic options for these viruses, Hendra and Nipah viruses caused zoonotic disease on a scale not seen before with ...
Kim, Halpin, Bruce A, Mungall
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