Results 121 to 130 of about 3,651 (163)

Sub-Nucleolar Trafficking of Hendra Virus Matrix Protein Is Regulated by Ubiquitination. [PDF]

Viruses
Zhao T, Gomez FA, David CT, Rootes CL, Stewart CR, Moseley GW, Rawlinson SM.   +6 more
europepmc   +1 more source

The E3 ligase RAD18-mediated ubiquitination of henipavirus matrix protein promotes its nuclear-cytoplasmic trafficking and viral egress. [PDF]

Emerg Microbes Infect
Jin D, Zhang L, Peng C, He M, Wang W, Li Z, Liu C, Du J, Zhou J, Yin L, Shan C, Qin Y, Chen M.   +12 more
europepmc   +1 more source

Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells. [PDF]

Viruses
Lenhard L, Müller M, Diederich S, Loerzer L, Friedrichs V, Köllner B, Finke S, Dorhoi A, Pei G.   +8 more
europepmc   +1 more source

Development of a semicomprehensive detection method for paramyxoviruses and its validation using Indonesian bats. [PDF]

Sci Rep
Nesti DR, Hayashida K, Sugi T, Artama WT, Wijayanto H, Kawai N, Yamagishi J.   +6 more
europepmc   +1 more source

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Ferret Models for Henipavirus Infection

2023
Henipaviruses are emerging zoonotic viruses that can cause outbreaks of severe respiratory and neurological disease in humans and animals such as horses. The mechanism by which these viruses can cause disease remain largely unknown and to date there are no therapeutics or vaccines approved for use in humans.
Rockx, Barry, Mire, Chad E.
openaire   +3 more sources

Mouse Models of Henipavirus Infection

2023
The Nipah and Hendra viruses, belonging to henipavirus genus, are recently emerged zoonotic pathogens that cause severe and often fatal, neurologic, and/or respiratory diseases in both humans and various animals. As mice represent a small animal model convenient to study viral infections and provide a well-developed experimental toolbox for analysis in
Iampietro, Mathieu, Barron, Stéphane, Duthey, Aurélie, Horvat, Branka   +3 more
openaire   +4 more sources

Profiling Host MicroRNA Responses to Henipavirus Infection

2023
Diseases caused by henipaviruses feature incubation periods of up to 16 days, during which infected animals may show no apparent signs of disease yet be capable of transmitting the virus to humans. This risk has prompted research into host-derived biomarkers for early disease detection. Here, we describe a methodology for the assaying of host microRNAs
Ryan J, Farr, Sudeep, Dahal, Leon, Tribolet, Andrew G D, Bean, Christopher, Cowled, Cameron R, Stewart   +5 more
openaire   +2 more sources

Animal models of henipavirus infection: A review

The Veterinary Journal, 2009
Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level four pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy.
Hana M, Weingartl, Yohannes, Berhane, Markus, Czub   +2 more
openaire   +2 more sources

Host Transcriptome Analysis of Ferret Tissues Following Henipavirus Infection

2023
Ferrets are commonly used as experimental models of infection for a variety of viruses due to their susceptibility to human respiratory viruses and the close resemblance of pathological outcomes found in human infections. Even though ferret-specific reagents are limited, the use of ferrets as a preclinical experimental model of infection has gained ...
Tian S, Zeng, D S, Yang, A A, Kelvin, David J, Kelvin   +3 more
openaire   +2 more sources

Overview of Experimental Vaccines and Antiviral Therapeutics for Henipavirus Infection

2023
Hendra virus (HeV) and Nipah virus (NiV) are highly pathogenic paramyxoviruses, which have emerged in recent decades and cause sporadic outbreaks of respiratory and encephalitic disease in Australia and Southeast Asia, respectively. Over two billion people currently live in regions potentially at risk due to the wide range of the Pteropus fruit bat ...
Benjamin A, Satterfield, Chad E, Mire, Thomas W, Geisbert   +2 more
openaire   +2 more sources